Protein Alignment KCNAB3 and CG3397

DIOPT Version :10

• Sequence 1: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_650140.1
• Gene: CG3397 / 41454
• FlyBaseID: FBgn0037975
• Length: 342
• Species: Drosophila melanogaster
• Alignment Length: 254
• Identity: 69/254 - (27%)
• Similarity: 104/254 - (40%)
• Gaps: 59/254 - (23%)

Human    78 MKYRNLGKSGLRVSCLGLGTWVTFGSQISD--ETAEDVLTV--AYEHGVNLFDTAEVYAAGKAER 138
            |:||.||.:|||||.:.|| ..|.....||  :..|.:|||  |...|:|..|||..|..||:|.
  Fly    22 MEYRQLGSTGLRVSKIALG-GATLSKLFSDDFDREEGILTVQEAIRSGINYIDTAPFYGQGKSEE 85

Human   139 TLGNILKSKGWRRSSYVITTKI------------FWGGQAETERGLSRKHIIEGLRGSLERLQLG 191
            .||..||..  .|.:|.|.||:            :...:|.           |.::.|||.|||.
  Fly    86 LLGQALKDV--PREAYYIATKVARYELDPNNMFDYTAAKAR-----------ESVKRSLELLQLD 137

Human   192 YVDIVFANRSD--PNCPM--EEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPV 252
            .||::..:..|  |:..|  .|.:..:...:..|.|.:.|.:.:....:.|.....:  ..|..|
  Fly   138 RVDVLQVHDVDAAPSLDMVLNETIPVLEEYVQAGKARFIGVTAYDVDVLKECAERGK--GRIQVV 200

Human   253 CEQAEHHLFQREKVEMQLPELYHKIGVGSV----------------TWYP-----LACG 290
            ...|.:.|.  :...::..:.:.::|||.|                :|:|     ||.|
  Fly   201 LNYARYTLL--DNTLLRHMKAFQEMGVGVVCAAAHSLGLLSNAGPQSWHPGSPELLAVG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	69/254 (27%)
CG3397	NP_650140.1	AKR_galDH	22..315	CDD:381389	69/254 (27%)