Protein Alignment KCNAB3 and CG12224

DIOPT Version :10

• Sequence 1: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_650139.4
• Gene: CG12224 / 41453
• FlyBaseID: FBgn0037974
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 235
• Identity: 67/235 - (28%)
• Similarity: 103/235 - (43%)
• Gaps: 40/235 - (17%)

Human    78 MKYRNLGKSGLRVSCLGLGTWVTFGSQISD------ETAEDVLTV--AYEHGVNLFDTAEVYAAG 134
            |:||.||.:||.||.|.:|     ||.:.:      :..|.:|.|  |...|:|..|||..|  |
  Fly    22 MEYRQLGSTGLHVSKLAIG-----GSPLCNLFFDDYDREEGILMVQEAIRSGINYIDTAPFY--G 79

Human   135 KAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHII--------EGLRGSLERLQLG 191
            ::|..||..||..  .|.:|.|.||:       ...||..|::.        |.::.|||||||.
  Fly    80 QSEVLLGQALKDV--PREAYYIATKV-------ARYGLDPKNMFDYSADKARESVKRSLERLQLD 135

Human   192 YVDIVFANRSD--PNCP--MEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPV 252
            .|||:..:..|  ||..  :.|.:..:...:..|.|.:.|.:.:....:.|.....:  ..|..|
  Fly   136 RVDILQVHDVDAAPNLDIVLNETIPVLEEYVQAGKARFIGVTAYDVDVLKECAERGK--GRIQVV 198

Human   253 CEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLI 292
            ...|.:.|.  :...::..:.:.|:|||.|.....:.||:
  Fly   199 LNYARYTLL--DNTLLRYMKDFQKMGVGVVCAAAHSLGLL 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	67/235 (29%)
CG12224	NP_650139.4	AKR_galDH	22..313	CDD:381389	67/235 (29%)