Protein Alignment KCNAB3 and CG18547

DIOPT Version :10

• Sequence 1: XP_047293000.1
• Gene: KCNAB3 / 9196
• HGNCID: 6230
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_650138.1
• Gene: CG18547 / 41452
• FlyBaseID: FBgn0037973
• Length: 345
• Species: Drosophila melanogaster
• Alignment Length: 232
• Identity: 64/232 - (27%)
• Similarity: 106/232 - (45%)
• Gaps: 30/232 - (12%)

Human    78 MKYRNLGKSGLRVSCLGLG---TWVTFGSQISDETAEDVLTV--AYEHGVNLFDTAEVYAAGKAE 137
            |:||||||:||:||.:..|   ....:|..:.    |.:.||  |.:.|:|..|||..|..|::|
  Fly    22 MEYRNLGKTGLQVSKVSFGGGALCANYGFDLE----EGIKTVHEAVKSGINYIDTAPWYGQGRSE 82

Human   138 RTLGNILKSKGWRRSSYVITTKIFWGGQAETER----GLSRKHIIEGLRGSLERLQLGYVDIV-- 196
            ..||..||..  .|.||.|.||:   .:.|.:.    ..|.|...|.:..||:.|.|.|||::
  Fly    83 EVLGLALKDV--PRESYYIATKV---ARYELDYDKMFDFSAKKTRESVEKSLKLLGLDYVDVIQI 142

Human   197 ----FANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAE 257
                ||  .|.:..:.|.:..:..::.:|.|.:.|.|.:..:.:.|  .:.|....:..|...|.
  Fly   143 HDIEFA--KDLDIVINETLPTLEQLVKEGKARFIGVSAYPISVLKE--FLTRTAGRLDTVLTYAR 203

Human   258 HHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITS 294
            :.|  .::..::..:.:....:|.:.....|.||:|:
  Fly   204 YTL--TDETLLEYLDFFKSQNLGVICAAAHALGLLTN 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNAB3	XP_047293000.1	AKR_SF	76..349	CDD:444925	64/232 (28%)
CG18547	NP_650138.1	AKR_galDH	22..314	CDD:381389	64/232 (28%)