Protein Alignment COG7 and cog7

DIOPT Version :9

• Sequence 1: NP_705831.1
• Gene: COG7 / 91949
• HGNCID: 18622
• Length: 770
• Species: Homo sapiens
• Sequence 2: NP_001015714.1
• Gene: cog7 / 548431
• XenbaseID: XB-GENE-970837
• Length: 768
• Species: Xenopus tropicalis
• Alignment Length: 770
• Identity: 583/770 - (75%)
• Similarity: 682/770 - (88%)
• Gaps: 2/770 - (0%)

Human     1 MDFSKFLADDFDVKEWINAAFRAGSKEAASGKADGHAATLVMKLQLFIQEVNHAVEETSHQALQN 65
            ||||:||||||:||:|:||||::..|:|.: |.|.||:||||||||||||||::|||.|||||||
 Frog     1 MDFSRFLADDFEVKDWVNAAFKSVQKDAPA-KVDAHASTLVMKLQLFIQEVNNSVEEISHQALQN 64

Human    66 MPKVLRDVEALKQEASFLKEQMILVKEDIKKFEQDTSQSMQVLVEIDQVKSRMQLAAESLQEADK 130
            ||:|||||||::||||||||||||||||||||||||:||||||||:|:|||||||||:|||||||
 Frog    65 MPRVLRDVEAVRQEASFLKEQMILVKEDIKKFEQDTAQSMQVLVEMDKVKSRMQLAADSLQEADK 129

Human   131 WSTLSADIEETFKTQDIAVISAKLTGMQNSLMMLVDTPDYSEKCVHLEALKNRLEALASPQIVAA 195
            |||||||||||||||:|.|||.|||.||.||.|||||||||||||:||||||||||:.|||||||
 Frog   130 WSTLSADIEETFKTQNITVISEKLTSMQVSLTMLVDTPDYSEKCVYLEALKNRLEAMCSPQIVAA 194

Human   196 FTSQAVDQSKVFVKVFTEIDRMPQLLAYYYKCHKVQLLAAWQELCQSDLSLDRQLTGLYDALLGA 260
            |.||:|||:|:|||||:||||||||||||||||||||:..||||||||:.||||||..||.||.|
 Frog   195 FNSQSVDQAKMFVKVFSEIDRMPQLLAYYYKCHKVQLVTVWQELCQSDMPLDRQLTEFYDTLLSA 259

Human   261 WHTQIQWATQVFQKPHEVVMVLLIQTLGALMPSLPSCLSNGVERAGPEQELTRLLEFYDATAHFA 325
            ||||:||.:|||:||.|||.||:||||.|::||:|.|||..:|||.||.:|:.|||.|:||.|||
 Frog   260 WHTQLQWVSQVFKKPQEVVTVLMIQTLAAMVPSIPVCLSTAMERASPEDKLSTLLELYNATGHFA 324

Human   326 KGLEMALLPHLHEHNLVKVTELVDAVYDPYKPYQLKYGDMEESNLLIQMSAVPLEHGEVIDCVQE 390
            |.:|.|:||::.|:||||:.||||||:.|||||||:|||:||||||||:||:|||.|||:|||||
 Frog   325 KSMETAILPNMGEYNLVKLIELVDAVFGPYKPYQLQYGDLEESNLLIQISAMPLERGEVLDCVQE 389

Human   391 LSHSVNKLFGLASAAVDRCVRFTNGLGTCGLLSALKSLFAKYVSDFTSTLQSIRKKCKLDHIPPN 455
            |||||::||.|||.|:|||::||:|||.||||.||:|||.|||:|||.||||||||||||:||.:
 Frog   390 LSHSVSRLFSLASGAMDRCIKFTDGLGLCGLLQALQSLFKKYVTDFTLTLQSIRKKCKLDNIPAD 454

Human   456 SLFQEDWTAFQNSIRIIATCGELLRHCGDFEQQLANRILSTAGKYLSDSCSPRSLAGFQESILTD 520
            |||.|||:|||||:|||..||||||.|||||||||:|.||.|||:|||:.|||||.|.||:..:|
 Frog   455 SLFLEDWSAFQNSVRIIGACGELLRQCGDFEQQLASRFLSIAGKHLSDTYSPRSLTGIQETSYSD 519

Human   521 KKNSAKNPWQEYNYLQKDNPAEYASLMEILYTLKEKGSSNHNLLAAPRAALTRLNQQAHQLAFDS 585
            :| |::|||.:||||||.:||:||:|||.||.|||||:.:.:||||.|:|.||.||.||||||||
 Frog   520 RK-SSRNPWHDYNYLQKGDPAQYANLMETLYMLKEKGAVSTSLLAASRSAFTRQNQVAHQLAFDS 583

Human   586 VFLRIKQQLLLISKMDSWNTAGIGETLTDELPAFSLTPLEYISNIGQYIMSLPLNLEPFVTQEDS 650
            |||.|||||||:.||:||:..|.||.||::||.|||||||||||||||:|||||:||||||.|||
 Frog   584 VFLHIKQQLLLVPKMESWSCEGSGEMLTEDLPTFSLTPLEYISNIGQYLMSLPLHLEPFVTPEDS 648

Human   651 ALELALHAGKLPFPPEQGDELPELDNMADNWLGSIARATMQTYCDAILQIPELSPHSAKQLATDI 715
            .|||||||||||||||||:|.||||||||.||||:||||||||||.||||..|:||:.|||||||
 Frog   649 TLELALHAGKLPFPPEQGEETPELDNMADYWLGSLARATMQTYCDVILQISLLTPHTTKQLATDI 713

Human   716 DYLINVMDALGLQPSRTLQHIVTLLKTRPEDYRQVSKGLPRRLATTVATMRSVNY 770
            ||||||||||||||:|||||||||||.:||:||.|:|.|||:|::::|.|||:.|
 Frog   714 DYLINVMDALGLQPTRTLQHIVTLLKAKPEEYRPVAKSLPRKLSSSIAAMRSLEY 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
COG7	NP_705831.1	COG7	2..767	CDD:287200	579/764 (76%)
cog7	NP_001015714.1	COG7	2..765	CDD:337664	579/764 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	1177	1.000	Domainoid score	I425
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H33431
Inparanoid	1	1.050	1182	1.000	Inparanoid score	I2291
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D198192at33208
OrthoFinder	1	1.000	-	-		FOG0007167
OrthoInspector	1	1.000	-	-		oto156304
Panther	1	1.100	-	-	LDO	PTHR21443
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4519
SonicParanoid	1	1.000	-	-		X5277
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.190