Protein Alignment BOC and tei

DIOPT Version :10

• Sequence 1: XP_047305129.1
• Gene: BOC / 91653
• HGNCID: 17173
• Length: 1152
• Species: Homo sapiens
• Sequence 2: NP_523731.2
• Gene: tei / 36521
• FlyBaseID: FBgn0000633
• Length: 822
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 113/603 - (18%)
• Similarity: 185/603 - (30%)
• Gaps: 212/603 - (35%)

Human    55 LGCVVEPPRMNVTWRLNGKELNGSD------DALGVLITHGTLVITALNNHTVGRYQCVARMPAG 113
            |.|.|:.......|..||:.::..|      |...:...:|.|.||.:.....|::||.|.....
  Fly   256 LMCEVDLDIATSMWYKNGQVVHAMDRTARVTDYRFIKEANGALTITNVMLEDDGKWQCEAENTRR 320

Human   114 AVASV-PATVTLAN--------LQDFKLDVQHV-IEVDEGNTAVIACHLPESHPKAQVRYSVKQE 168
            ...:. |..:.:.:        :...:||..:: :.|.|.:...:||.....:|:..:.:.|
  Fly   321 YTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNPRPTLTWEV--- 382

Human   169 WLEASRGNYLIMPSGN------------LQIVNASQEDEGMYKCAAYNPVTQEVKTSG--SSDRL 219
                     |:.|..:            |:.:...:.|:..||.           .||  |..||
  Fly   383 ---------LLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKI-----------NSGAKSEARL 427

Human   220 RVRRSTAEAARIIYPPEAQTIIVTKGQSLILE----------------------------CVASG 256
            .........|||:...|..|:.:.:..||:|:                            |....
  Fly   428 PAVYRAHHNARILCVMEHPTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDS 492

Human   257 IPPPRVTWAKDGSSV----TGYNKTRFLLSNLLIDTTSEEDSGTYRCMAD------NGVGQPGAA 311
            .||....|.||....    ||.....|       .:...|.||.|:|.:.      :.:|
  Fly   493 NPPSTPRWQKDDGDTPVPQTGDGFLNF-------TSIRREHSGWYKCTSRHLNFQYSSIG----- 545

Human   312 VILYNVQV-FEPPEVTME----------------LSQLVIPWGQSAKLTCEVRGNPPPSVLWLRN 359
               |.:.| |:..:||.|                ..||.:..|.:..|.|      |...|...:
  Fly   546 ---YYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQC------PQGSLGCWS 601

Human   360 AVPLISSQRLRLSRRALRVLSMGP--------------EDEGVYQCMAEN--------------- 395
            .:..||::        ||.|..|.              :|.|:|:|:.::
  Fly   602 HLDPISAR--------LRGLGYGSSQPTGQFSLKDVMYQDAGMYKCVGQSPTNKKKLEVLQSVTV 658

Human   396 EVGSAHAVVQLRTSRPSPPGITPRLWQDAELATGTPPVSPSKLGNPEQMLRGQPALPRPPTSVGP 460
            .|..|..|:.|..:..:.|| :| |..:.|.....|       .:..:.|.|....
  Fly   659 SVKGAPTVMALNATPVAYPG-SP-LHLNVEFCANPP-------AHAARWLHGDRVF--------- 705

Human   461 ASPQCPGEK-GQGAPAEAPIILSSPRTSKTDSYELVWRPRHEGSGRAPILYYVV----------- 513
                .||.: |....|.|...|.:|...:.   .|.:...||   |.|..:|.:
  Fly   706 ----TPGNQYGTTVLAYAVKDLPTPFCKEA---RLTYVSMHE---RVPRTFYFIVSTPGGVAEAI 760

Human   514 ------KHRKQVTNSSDD 525
                  |..:|::||.||
  Fly   761 FNVNFTKRHRQLSNSIDD 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BOC	XP_047305129.1	Ig_3	36..109	CDD:464046	15/59 (25%)
		Ig	129..204	CDD:472250	14/87 (16%)
		Ig strand B	146..150	CDD:409353	0/3 (0%)
		Ig strand C	160..164	CDD:409353	0/3 (0%)
		Ig strand E	183..187	CDD:409353	1/15 (7%)
		Ig strand F	197..202	CDD:409353	2/4 (50%)
		Ig	239..306	CDD:472250	18/104 (17%)
		Ig strand B	248..252	CDD:409353	2/31 (6%)
		Ig strand C	261..265	CDD:409353	0/3 (0%)
		Ig strand E	276..286	CDD:409353	1/9 (11%)
		Ig strand F	296..301	CDD:409353	2/4 (50%)
		Ig	323..406	CDD:472250	23/127 (18%)
		Ig strand B	340..344	CDD:409353	1/3 (33%)
		Ig strand C	353..357	CDD:409353	1/3 (33%)
		Ig strand E	374..378	CDD:409353	1/3 (33%)
		Ig strand F	388..393	CDD:409353	2/4 (50%)
		Ig strand G	401..404	CDD:409353	0/2 (0%)
		ISET-FN3_linker	414..476	CDD:435475	11/62 (18%)
		FN3	<474..>766	CDD:442628	16/69 (23%)
		FN3	610..701	CDD:238020
		FN3	716..813	CDD:238020
tei	NP_523731.2	IG_like	244..332	CDD:214653	17/75 (23%)
		Ig strand B	254..258	CDD:409353	1/1 (100%)
		Ig strand C	267..271	CDD:409353	1/3 (33%)
		Ig strand E	296..300	CDD:409353	2/3 (67%)
		Ig strand F	310..315	CDD:409353	2/4 (50%)
		Ig strand G	326..329	CDD:409353	1/2 (50%)
		Ig	359..452	CDD:472250	21/115 (18%)
		Ig_3	478..533	CDD:464046	13/61 (21%)
		IG_like	578..660	CDD:214653	17/95 (18%)