DRSC/TRiP Functional Genomics Resources

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Protein Alignment ANKRD44 and NAS6

DIOPT Version :9

Sequence 1:NP_001354424.1 Gene:ANKRD44 / 91526 HGNCID:25259 Length:1074 Species:Homo sapiens
Sequence 2:NP_011748.3 Gene:NAS6 / 853147 SGDID:S000003464 Length:228 Species:Saccharomyces cerevisiae


Alignment Length:218 Identity:69/218 - (31%)
Similarity:104/218 - (47%) Gaps:30/218 - (13%)


- Green bases have known domain annotations that are detailed below.


Human   517 ELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLL---ERTNSGFE 578
            |..:.:||...:.:|.|:           :|::|...:|::.::...:....||   |..|....
Yeast    14 EFFKVQELLHSKPSLLLQ-----------KDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDY 67

Human   579 ESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDE------KGRTALDLAAFKGHTECVEAL 637
            ..|||.|  |.|:|...|:   ||| ::||.|..::.:      :|.|.|.||..|...|..:.|
Yeast    68 PDDSGWT--PFHIACSVGN---LEV-VKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFL 126

Human   638 INQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHID 702
            |..|||:.:||.. .:.|||.:...|....:.||..:..:  ||:.:|.:|.|||..|:|.||.|
Yeast   127 IENGASVRIKDKF-NQIPLHRAASVGSLKLIELLCGLGKS--AVNWQDKQGWTPLFHALAEGHGD 188

Human   703 AVSLLLEK-EANVDTVDILGCTA 724
            |..||:|| .|..|.||..|..|
Yeast   189 AAVLLVEKYGAEYDLVDNKGAKA 211

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ANKRD44NP_001354424.1 ANK 1 7..36
ANK 2 40..69
ANK 3 73..102
ANK 4 106..135
ANK 5 139..168
ANK 6 172..201
ANK 7 205..234
ANK 8 238..267
ANK 9 271..301
ANK 10 305..334
ANK 11 338..367
ANK 13 422..451
ANK 14 455..484
ANK 15 488..516
ANK 16 549..579 6/32 (19%)
ANK 17 584..613 11/28 (39%)
ANK 18 617..646 12/28 (43%)
ANK 19 651..680 6/28 (21%)
ANK 20 687..716 15/29 (52%)
ANK 21 720..749 2/5 (40%)
ANK 22 753..782
ANK 23 789..818
ANK 24 821..850
ANK 25 856..885
ANK 26 889..919
ANK 27 923..952
ANK 28 959..988
NAS6NP_011748.3 ANKYR 1..226 CDD:223738 69/218 (32%)
ANK repeat 1..33 CDD:293786 5/29 (17%)
ANK repeat 35..69 CDD:293786 6/33 (18%)
ANK repeat 71..104 CDD:293786 13/38 (34%)
ANK repeat 107..137 CDD:293786 12/29 (41%)
ANK repeat 139..171 CDD:293786 8/34 (24%)
ANK repeat 173..205 CDD:293786 16/31 (52%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100012
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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