DRSC/TRiP Functional Genomics Resources

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Protein Alignment CCNE2 and CycA

DIOPT Version :10

Sequence 1:NP_477097.1 Gene:CCNE2 / 9134 HGNCID:1590 Length:404 Species:Homo sapiens
Sequence 2:NP_524030.2 Gene:CycA / 39340 FlyBaseID:FBgn0000404 Length:491 Species:Drosophila melanogaster


Alignment Length:256 Identity:78/256 - (30%)
Similarity:127/256 - (49%) Gaps:40/256 - (15%)


- Green bases have known domain annotations that are detailed below.


Human   136 DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200
            |:...|||||:|||:||.|.|.|..||.||:..:.||| |:|..:.::.|||:|..:::||:|.|
  Fly   230 DISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRF-LSQMAVVRSKLQLVGTAAMYIAAKYE 293

Human   201 EIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLP 265
            |||.|::.||.::||.:.::..:||||.:|||.|.::||..|...::|.:.   .|.|.|:.|  
  Fly   294 EIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYVFINTYA---VLCDMPEKL-- 353

Human   266 QYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLE-WDSISECVDWMV 329
                       :.:.|.|..:..:|.:..:....:|....|:.:.:...|:| |....|      
  Fly   354 -----------KYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLE------ 401

Human   330 PFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH-----TNYLAMLEEVNYINTFRKGGQLSPV 385
                   ..:..||:..|.:.:   |...||     .|..||.|:.|. :|::|...:..|
  Fly   402 -------EITTYKLEDLKTVVL---HLCHTHKTAKELNTQAMREKYNR-DTYKKVAMMESV 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CCNE2NP_477097.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..44
CYCLIN_CCNE2_rpt1 100..236 CDD:410283 47/99 (47%)
CYCLIN_CCNE2_rpt2 240..338 CDD:410285 15/98 (15%)
CycANP_524030.2 CYCLIN_CCNA_rpt1 202..329 CDD:410208 47/99 (47%)
Cyclin_C 334..450 CDD:397230 28/148 (19%)
Blue background indicates that the domain is not in the aligned region.

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