Protein Alignment CCNE2 and CycD

DIOPT Version :10

• Sequence 1: NP_477097.1
• Gene: CCNE2 / 9134
• HGNCID: 1590
• Length: 404
• Species: Homo sapiens
• Sequence 2: NP_523355.2
• Gene: CycD / 32551
• FlyBaseID: FBgn0010315
• Length: 477
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 77/325 - (23%)
• Similarity: 135/325 - (41%)
• Gaps: 60/325 - (18%)

Human     2 SRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPPVLSGGI 66
            ::...:|:....|.|.....|...|.||:..|..:|:                    ||.
  Fly    77 AKNPEQLEPPPPPPPPPPPPPTATQSIQSYPRYISQE--------------------PPT----- 116

Human    67 SPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKKESRY--VHDKH 129
            |.|..::  .:...|:|.....|.   |..|....|  .|..|.:    |.||.|.::  :.|.:
  Fly   117 SHCQRLD--ERLTTTADPPATDNV---NTAIGDPTL--YSDRCLE----NFLKVEEKHHKIPDTY 170

Human   130 FEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLF 194
            |.: ..|:.|.||.|:.:|::|||.......|...||.::.||| |:.|.:.|..||::....|.
  Fly   171 FSI-QKDITPPMRKIVAEWMMEVCAEENCQEEVVLLALNYMDRF-LSSKSVRKTQLQILAAACLL 233

Human   195 IASKLEE--IYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDAL- 256
            :||||.|  ..|..:......||.:..::|:::.||.:|..|.|:|..||.:.:|.|.:....:
  Fly   234 LASKLREPSCRALSVDLLVVYTDNSIYKDDLIKWELYVLSRLGWDLSSVTPLDFLELLMMRLPIG 298

Human   257 -KDAPKVLLPQY--SQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEW 318
             |:.|.:.:.:.  ..:.||.:|           :.|.::...:|:.:   .:..:....:||:|
  Fly   299 SKNFPDINIGKVRGHAQAFISLA-----------AKEHKFAKFSASTI---AASSIAASMNGLKW 349

Human   319  318
              Fly   350  349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNE2	NP_477097.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..44		9/41 (22%)
		CYCLIN_CCNE2_rpt1	100..236	CDD:410283	43/139 (31%)
		CYCLIN_CCNE2_rpt2	240..338	CDD:410285	14/83 (17%)
CycD	NP_523355.2	CYCLIN_SF	144..278	CDD:477360	43/141 (30%)
		CYCLIN_CCND_rpt2	283..387	CDD:410220	13/81 (16%)