Protein Alignment CCNB2 and CycG

DIOPT Version :10

• Sequence 1: NP_004692.1
• Gene: CCNB2 / 9133
• HGNCID: 1580
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_524609.2
• Gene: CycG / 43724
• FlyBaseID: FBgn0039858
• Length: 566
• Species: Drosophila melanogaster
• Alignment Length: 323
• Identity: 65/323 - (20%)
• Similarity: 118/323 - (36%)
• Gaps: 77/323 - (23%)

Human    80 PVQMEKLAPKGPSPTP----------------EDVSMKEENLC------QAFSDALLCKIEDIDN 122
            |....::|.:|...||                ||::..|....      ...|.:.|.|:||
  Fly   169 PTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSLKKLED--- 230

Human   123 EDWENPQLCSDYVKDIYQYLRQLEVLQ------------SINPHFLDGRDINGRMRAILVDWLVQ 175
               :...|.||   ::|:.|::.:|||            |.......|||.:..:...|..|
  Fly   231 ---QLHALTSD---ELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMW--- 286

Human   176 VHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNA 240
                :.|..:.|:..:.::||||....|..|.:..:.:.:..||.|..::.....||.|.|:...
  Fly   287 ----YELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCG 347

Human   241 YTSSQIREMETLILKELKFELGRP-------LPLHFLRRASKAGEVDVEQHTLAKYL-------- 290
            .|:..:..|..:|..:|..::|..       |.:::....:.|.|:..:.....:.|
  Fly   348 CTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELEN 412

Human   291 -MELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTE-----NEVLEVMQHM 347
             :|:.:.|.......||.:|....||..      .:::|:.|..|..|     ..:|.:.|:|
  Fly   413 RLEILMCDVKTTVITPSTLALVLICLHL------DFHIKESYTRGSPELKHVFEYILFLQQYM 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNB2	NP_004692.1	CYCLIN_CCNB2_rpt1	127..259	CDD:410269	33/143 (23%)
		CYCLIN_CCNB2_rpt2	264..382	CDD:410273	18/105 (17%)
CycG	NP_524609.2	CYCLIN_CCNG	273..364	CDD:410227	22/97 (23%)