Protein Alignment CCNB2 and CycB3

DIOPT Version :9

• Sequence 1: NP_004692.1
• Gene: CCNB2 / 9133
• HGNCID: 1580
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_001262934.1
• Gene: CycB3 / 42971
• FlyBaseID: FBgn0015625
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 123/405 - (30%)
• Similarity: 197/405 - (48%)
• Gaps: 67/405 - (16%)

Human     4 LRRPTVSS--DLENIDTGVNSKVKSHVTIRRTVLEEI---------GNRVTTRAAQVAKKAQNTK 57
            |..|.|::  .:..|....|   |:..::..:.||::         ||....| .:.||..|.|:
  Fly   200 LAAPQVAAVKPVRRISNDFN---KTEDSLYMSALEDVSSCDSMRLSGNFEAAR-RRSAKLQQKTE 260

Human    58 VPVQPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDN 122
            ...||...|     |..||   |.|:..:     .|.||:|                   ||.|.
  Fly   261 QQPQPLLLT-----LPETA---PSQVVPI-----PPVPEEV-------------------EDFDR 293

Human   123 EDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETL 187
            ::|::|...|.|..||:.||:..|....|..:......:...||.:||||:|:|...|.|..|||
  Fly   294 KNWDDPFQVSHYAMDIFNYLKVREAEFPIADYMPRQIHLTTWMRTLLVDWMVEVQETFELNHETL 358

Human   188 YMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETL 252
            |:.|.|:|.:|..:.::::||||:|..|..:|.||:|...|.||||:||.|.||...::..||..
  Fly   359 YLAVKIVDLYLCREVINKEKLQLLGAAAFFIACKYDERQPPLIEDFLYICDGAYNHDELVRMERE 423

Human   253 ILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQ 317
            .|:.:|::||.||...||||.::..:|.:...|||:|::||:|:||..:.:..|::|:||..::.
  Fly   424 TLRVIKYDLGIPLSYRFLRRYARCAKVPMPTLTLARYILELSLMDYANISFSDSQMASAALFMAL 488

Human   318 KVLGQGKWNLKQQ-------YYTGYTENEVLEVMQHMAKNVVKVNENLTK-----FIAIKNKYAS 370
            ::.| |...|.:|       |||||...:..|:       |..:|..|.:     ...|:|||:.
  Fly   489 RMHG-GPGQLDKQTWTSTLIYYTGYQLADFAEI-------VTALNAGLHRKPRATIKTIRNKYSH 545

Human   371 SKLLKISMIPQLNSK 385
            ....:::.:|.|.::
  Fly   546 KIFHEVAKVPLLTNQ 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNB2	NP_004692.1	Cyclin_N	137..262	CDD:278560	48/124 (39%)
		Cyclin_C	264..382	CDD:281044	38/129 (29%)
CycB3	NP_001262934.1	Cyclin_N	308..433	CDD:278560	48/124 (39%)
		Cyclin_C	435..555	CDD:281044	37/127 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D475911at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R194
SonicParanoid	1	1.000	-	-		X94
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850