Protein Alignment CCNB2 and CycA

DIOPT Version :10

• Sequence 1: NP_004692.1
• Gene: CCNB2 / 9133
• HGNCID: 1580
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_524030.2
• Gene: CycA / 39340
• FlyBaseID: FBgn0000404
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 372
• Identity: 106/372 - (28%)
• Similarity: 184/372 - (49%)
• Gaps: 33/372 - (8%)

Human    14 ENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQNTKVPVQPTKTTNVNKQLKPTASV 78
            :|.||.|....||..::    :::..:.|...|.|  |:..:..:...|...|:|...:....|:
  Fly   104 DNNDTQVAPSGKSLASL----VDKENHDVKFGAGQ--KELVDYDLDSTPMSVTDVQSPMSVDRSI 162

Human    79 KPV-QMEKLA---PKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIY 139
            ..| |...::   ..|.|||.....:...|..|.|.:.:                   .|..||.
  Fly   163 LGVIQSSDISVGTETGVSPTGRVKELPPRNDRQRFLEVV-------------------QYQMDIL 208

Human   140 QYLRQLEVLQSINPHFL-DGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPV 203
            :|.|:.|......|.:: ..:||:..||:||:||||:|..:::|..||||:.|..:||||....|
  Fly   209 EYFRESEKKHRPKPLYMRRQKDISHNMRSILIDWLVEVSEEYKLDTETLYLSVFYLDRFLSQMAV 273

Human   204 SRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLH 268
            .|.||||||..|:.:|:||||::.|.:.:||::||::||.:|:..||.:|||.|.|:|..|....
  Fly   274 VRSKLQLVGTAAMYIAAKYEEIYPPEVGEFVFLTDDSYTKAQVLRMEQVILKILSFDLCTPTAYV 338

Human   269 FLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKVLGQGKWNLKQQYY 332
            |:...:...::..:...:..|:.||:|::.: .:.|.||.:::|:..|::.:||...|..:.:..
  Fly   339 FINTYAVLCDMPEKLKYMTLYISELSLMEGETYLQYLPSLMSSASVALARHILGMEMWTPRLEEI 403

Human   333 TGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI 379
            |.|...::..|:.|:........|..|:  |::.||......|::|:
  Fly   404 TTYKLEDLKTVVLHLCHTHKTAKELNTQ--AMREKYNRDTYKKVAMM 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNB2	NP_004692.1	CYCLIN_CCNB2_rpt1	127..259	CDD:410269	56/132 (42%)
		CYCLIN_CCNB2_rpt2	264..382	CDD:410273	25/117 (21%)
CycA	NP_524030.2	CYCLIN_CCNA_rpt1	202..329	CDD:410208	56/126 (44%)
		Cyclin_C	334..450	CDD:397230	25/117 (21%)