Protein Alignment CCNB2 and CycJ

DIOPT Version :10

• Sequence 1: NP_004692.1
• Gene: CCNB2 / 9133
• HGNCID: 1580
• Length: 398
• Species: Homo sapiens
• Sequence 2: NP_523903.1
• Gene: CycJ / 38428
• FlyBaseID: FBgn0010317
• Length: 386
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 86/316 - (27%)
• Similarity: 128/316 - (40%)
• Gaps: 72/316 - (22%)

Human   117 IEDIDNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFR 181
            :|.:....|     .:||.:||:..:|:.|:  |..|.|.....:|.|.|  ::..|....|..:
  Fly    27 VERLAKTHW-----LTDYARDIFLTMREQEL--SRRPLFYLSPQLNERRR--MLQLLKLATSAHK 82

Human   182 LLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYE--EMFSPNIEDFVYITDNAYTSS 244
            |.:..|::.|..||||:....:...||.||.||.|.:|::.|  :.|.|...:...:..||||:.
  Fly    83 LSRCALHLAVYYMDRFVDYYKIRPDKLLLVAITCLHIAAQIENTDAFIPRYSEMNRLVKNAYTAF 147

Human   245 QIREMETLILKELKFELGRP--------LPLHFLRRA------SKAGEVDVEQHT---------- 285
            :.:.:|..||..|.|||.||        ....||.|:      ....|.:...||
  Fly   148 EYKAVERKILCFLNFELIRPTTASFVELFACSFLTRSDFKNYIEMLDEYERNHHTQPYQRYISFE 212

Human   286 -----LAKYLMELTLIDYDM-----VHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEV 340
                 ||:.|  |.:.||.:     .:..||.:|||.....::|.|..:|:......|.|||..|
  Fly   213 EMLSILAQLL--LRMADYTLYISRFANDLPSLLAAACIAAVRQVSGVRRWSEYLVGLTSYTEANV 275

Human   341 LEVMQHMAKNVVKVNENLTKFI---AIKNKYASSKLLKISMIPQLNSKAVKDLASP 393
            ...|     ||      ||.:.   .|:..|.|..:       |.|    :.||||
  Fly   276 EPYM-----NV------LTDYYYYHVIQTDYGSPSV-------QTN----QSLASP 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCNB2	NP_004692.1	CYCLIN_CCNB2_rpt1	127..259	CDD:410269	40/133 (30%)
		CYCLIN_CCNB2_rpt2	264..382	CDD:410273	34/154 (22%)
CycJ	NP_523903.1	CYCLIN_CCNJ-like_rpt1	61..162	CDD:410231	31/102 (30%)
		CYCLIN_CCNJ-like_rpt2	167..282	CDD:410232	29/127 (23%)