| Sequence 1: | NP_004691.2 | Gene: | KCNQ4 / 9132 | HGNCID: | 6298 | Length: | 695 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_741819.1 | Gene: | kqt-1 / 180933 | WormBaseID: | WBGene00002233 | Length: | 740 | Species: | Caenorhabditis elegans |
| Alignment Length: | 698 | Identity: | 276/698 - (39%) |
|---|---|---|---|
| Similarity: | 379/698 - (54%) | Gaps: | 136/698 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Human 27 TAVQSEQGEAGGGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVL 91
Human 92 ERPRGW-AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAG 155
Human 156 CCCRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRR 220
Human 221 GGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWGTITLTTIG 285
Human 286 YGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAW 350
Human 351 RLYSTDMSRAYLTATWYYYDSILPSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPV 415
Human 416 ATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSP--------------S 466
Human 467 SEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRTSAED--------APSEEVAEEK---SYQCE 520
Human 521 LTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQ 585
Human 586 IVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSA 650
Human 651 SLGAVQVPLFDPDITSDYHSPVDHEDISVSA-QTLSISR--SVSTNMD 695 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KCNQ4 | NP_004691.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..21 | ||
| MIG-14_Wnt-bd | <92..190 | CDD:284153 | 50/98 (51%) | ||
| Ion_trans | 126..330 | CDD:278921 | 129/203 (64%) | ||
| Ion_trans_2 | 246..320 | CDD:285168 | 51/73 (70%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 283..288 | 3/4 (75%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 400..480 | 16/93 (17%) | |||
| KCNQ_channel | 474..653 | CDD:281513 | 62/189 (33%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 496..515 | 4/26 (15%) | |||
| A-domain (Tetramerization) | 546..650 | 41/103 (40%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 587..606 | 4/18 (22%) | |||
| kqt-1 | NP_741819.1 | Ion_trans | 173..379 | CDD:278921 | 128/205 (62%) |
| Ion_trans_2 | 297..371 | CDD:285168 | 51/73 (70%) | ||
| KCNQ_channel | <540..651 | CDD:281513 | 52/131 (40%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 285 | 1.000 | Domainoid score | I964 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 458 | 1.000 | Inparanoid score | I963 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S4661 |
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1168835at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 1 | 1.000 | - | - | otm16077 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102886 | |
| Panther | 1 | 1.100 | - | - | O | PTHR11537 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4953 |
| SonicParanoid | 1 | 1.000 | - | - | X604 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.950 | |||||