Protein Alignment SMC3 and SMC3

DIOPT Version :10

• Sequence 1: NP_005436.1
• Gene: SMC3 / 9126
• HGNCID: 2468
• Length: 1217
• Species: Homo sapiens
• Sequence 2: NP_523374.2
• Gene: SMC3 / 32627
• FlyBaseID: FBgn0015615
• Length: 1200
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 59/311 - (18%)
• Similarity: 111/311 - (35%)
• Gaps: 93/311 - (29%)

Human    51 CLLCSTLAWQQHLRDAVSSLKIAERVQGELFASRTLSSWGS-AAAASGDSIECYTDIPKIIYA-- 112
            ||:|.:.|..::. .|:|....      ::|.:|...::.. .........|.:|.:||..:.
  Fly     3 CLVCCSYASSRNF-GALSCSAC------KMFFTRATKNYAKFTCKYDKKCFESFTILPKCQFCRF 60

Human   113 ------SRTHSQLTQVIRELRNTAYRPKVCVLGSREQLCIHPEVKKQESNHMQISLCRKKVASRS 171
                  ....|:..|.:..|.|:..:..:.:||:   |.:...|  ..||.:
  Fly    61 KKCLEIGMRFSEPKQQLFNLNNSVDQDLIILLGN---LAVKDGV--HYSNFL------------- 107

Human   172 CHFYNNVEAKFLEQDLATPILDIEDLVKNGSKQKMC-----------------PYYLSRNMKQQA 219
             :||:          |..|.:|  |::.:.|:.|:.                 .||   .:.|..
  Fly   108 -NFYS----------LEDPSMD--DILADRSRMKLMKRTLEIKTKSHEWTFLGSYY---KIAQFL 156

Human   220 DIIFMPYNYLLDAKSRKAHSIDLKGTVVIFDEAHNVEKICEESAS------------FDLTPRDV 272
            |..|:....|.|.|...:::....|::......:..::.|..:.|            ||.||
  Fly   157 DFDFVKTMSLADRKILFSYNTLRMGSLSRSMRTYLDKRDCLMTPSGDDLFSPAVRGLFDKTP--- 218

Human   273 ASGLEIINQVLEE------QARVTQQGELQQEFIVDTSSSGLNMELEDIAK 317
                ||||::|.:      :.::|.:..|....||..:.| ::.||.|.|:
  Fly   219 ----EIINRILCQVVGRLMEIKITYEEYLLLIMIVFCNPS-ISHELSDSAR 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMC3	NP_005436.1	SMC_N	2..1197	CDD:426784	59/311 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	242..268		5/37 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1059..1090
SMC3	NP_523374.2	SMC_N	2..1180	CDD:426784	59/311 (19%)