Protein Alignment SLC16A4 and CG8389

DIOPT Version :9

• Sequence 1: NP_004687.1
• Gene: SLC16A4 / 9122
• HGNCID: 10925
• Length: 487
• Species: Homo sapiens
• Sequence 2: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 468
• Identity: 86/468 - (18%)
• Similarity: 177/468 - (37%)
• Gaps: 61/468 - (13%)

Human    16 DGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMS-SLRFCAGPLVAI 79
            |||:||::|....|:|:....:...|...||...::.:..:.....|.::.| :|.| :|..:..
  Fly    11 DGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNF-SGLFIGP 74

Human    80 ICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRL 144
            .......:..:..|..:|..|..:.::|:......:......|.|...:.....:....||..:.
  Fly    75 AIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTKR 139

Human   145 ALSTAIARSGMGLTFLLAP-FTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGI 208
            ..:..::.:|.||..:|.| ..::|:|.:.:..|::...:::|..:..:..|:|:
  Fly   140 GRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPL---------- 194

Human   209 KDKGSSLSAHGPEAHATETHCH-ETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLL 272
                     :.|..|....|.. .||....|.|..|...:|:       |||:...:.||.:.|.
  Fly   195 ---------NPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPT-------NQSKIERSPPNVDTLC 243

Human   273 LKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVA-----RAKTLGID 332
            .:..:.        ..|..|:.|.::..|    ||.::.....:..|.:...     ..:|..::
  Fly   244 SRMGQR--------LVQAMDLELLKDLVF----WSIIVGMALVYTATINFTMIFPGFLGQTAQLN 296

Human   333 IMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSY--LILCGITNLLAPLAT-----TFP 390
            ....::.:|:....:.|.:::...|.|       |....|  :.|.||..|......     |.|
  Fly   297 SQMVAFCMSLVAGADIVFRLLLPIVTD-------HLRIPYRVVFLIGIVGLFVARCVLAENQTLP 354

Human   391 LLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTY 455
            :::|.::...:.....:......:...||:..:...|||:....|:.|::...:.||:.||..:|
  Fly   355 VIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSY 419

Human   456 NGSFYFSGICYLL 468
            ....|..|:..|:
  Fly   420 LICLYAQGVILLV 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A4	NP_004687.1	MFS	24..477	CDD:119392	81/460 (18%)
		MFS_1	27..442	CDD:284993	72/429 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..250		9/44 (20%)
CG8389	NP_611076.2	MFS	19..425	CDD:119392	78/451 (17%)
		MFS_1	19..400	CDD:284993	71/426 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820