Protein Alignment ATP6V0D1 and VhaAC39-2

DIOPT Version :10

• Sequence 1: NP_004682.2
• Gene: ATP6V0D1 / 9114
• HGNCID: 13724
• Length: 351
• Species: Homo sapiens
• Sequence 2: NP_651128.1
• Gene: VhaAC39-2 / 42739
• FlyBaseID: FBgn0039058
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 345
• Identity: 154/345 - (44%)
• Similarity: 233/345 - (67%)
• Gaps: 1/345 - (0%)

Human     7 LYFNVDNGYLEGLVRGLKAGVLSQADYLNLVQCETLEDLKLHLQSTDYGNFLANEASPLTVSVID 71
            :.||.:.||||.|.||.|.|:|..:|||||.|||:|||:.:.:|.||||.....|.|..:|.||:
  Fly     3 MIFNTEYGYLEALTRGFKNGMLKHSDYLNLTQCESLEDVMISIQGTDYGLIFGGEQSAPSVEVIE 67

Human    72 DRLKEKMVVEFRHMRNHAYEPLASFLDFITYSYMIDNVILLITGTLHQRSIAELVPKCHPLGSFE 136
            ..|:::::.::.::|:|:.|||.:|::||.|.:|||||.||:.|..:.||:..|:..|||||.|:
  Fly    68 RCLRDRLLQQYYYIRSHSTEPLTTFMEFIRYPFMIDNVALLVAGLNNHRSMKRLLRMCHPLGEFD 132

Human   137 QMEAVNIAQTPAELYNAILVDTPLAAFFQDCISEQDLDEMNIEIIRNTLYKAYLESFYKFCTLLG 201
            |:.|:.:|...|||::|:|:|||:|.|....:..:.|..:::||:|..||:||||.||.:|:.||
  Fly   133 QLGAIEVASNSAELFDAVLIDTPIARFVPRDLPMESLRYLDVEIVRAHLYRAYLEKFYAYCSQLG 197

Human   202 GTTADAMCPILEFEADRRAFIITINSFGTELSKEDRAKLFPHCGRLYPEGLAQLARADDYEQVKN 266
            |.||:.|..:|.||||||...|.:|:.|:::..::|.|:||.||.|....||.::..:|.:::::
  Fly   198 GNTANVMTNLLSFEADRRTITIAVNAIGSDIIPKERLKMFPTCGYLPKIALASMSTLNDTDKIRD 262

Human   267 VADYYPEYKLLFEG-AGSNPGDKTLEDRFFEHEVKLNKLAFLNQFHFGVFYAFVKLKEQECRNIV 330
            |.:.:..|..:|:. ...:.|..||||||...|.|.|...||.|:|||:||:|:|||:.|.||||
  Fly   263 VCNVFDGYGKMFDNLERDSDGMITLEDRFLMMEAKKNVQTFLQQYHFGIFYSFIKLKQLEVRNIV 327

Human   331 WIAECIAQRHRAKIDNYIPI 350
            ||:||||||...:|:.:|||
  Fly   328 WISECIAQRQTDRINAFIPI 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V0D1	NP_004682.2	vATP-synt_AC39	16..344	CDD:426553	146/328 (45%)
VhaAC39-2	NP_651128.1	vATP-synt_AC39	12..341	CDD:426553	146/328 (45%)