Protein Alignment SLC25A46 and slc25a46

DIOPT Version :10

• Sequence 1: NP_620128.1
• Gene: SLC25A46 / 91137
• HGNCID: 25198
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_001002558.1
• Gene: slc25a46 / 436831
• ZFINID: ZDB-GENE-040718-296
• Length: 405
• Species: Danio rerio
• Alignment Length: 424
• Identity: 297/424 - (70%)
• Similarity: 349/424 - (82%)
• Gaps: 28/424 - (6%)

Human     1 MHPRRPDGFDGLGYRGGARDEQGFGGAFPARSF--STGSDLGHWVTTPPDIPGSRNLHWGEKSPP 63
            |..||||.|:||||||  |::..|.|.:..|||  |:.|||.:|||||||||||||||:.:::|.
Zfish     1 MTSRRPDSFEGLGYRG--REDPAFSGGYSGRSFNNSSSSDLQNWVTTPPDIPGSRNLHFDDRTPQ 63

Human    64 YGVPTTSTPYEGPTEEPFSSGGGGSVQGQSSEQLNRFAGFGIGLASLFTENVLAHPCIVLRRQCQ 128
            :    .:.|.|..:..|            .|||||||||||||||||||||||||||||.|||||
Zfish    64 F----ETAPDEAQSAAP------------PSEQLNRFAGFGIGLASLFTENVLAHPCIVFRRQCQ 112

Human   129 VNYHAQHYHLTPFTVINIMYSFNKTQGPRALWKGMGSTFIVQGVTLGAEGIISEFTPLPREVLHK 193
            |||||:.|||:|.|.|::||:..|||||:||||||||||:|||||||.||||||.||||||:.||
Zfish   113 VNYHARCYHLSPMTAISVMYNVTKTQGPKALWKGMGSTFVVQGVTLGTEGIISECTPLPRELSHK 177

Human   194 WSPKQIGEHLLLKSLTYVVAMPFYSASLIETVQSEIIRDNTGILECVKEGIGRVIGMGVPHSKRL 258
            |:|||:..||:||.||||||||||||||||||||||||||.|||:|||||:|||:|||:||||||
Zfish   178 WNPKQVVGHLVLKGLTYVVAMPFYSASLIETVQSEIIRDNPGILDCVKEGLGRVMGMGIPHSKRL 242

Human   259 LPLLSLIFPTVLHGVLHYIISSVIQKFVLLILKRKTYNSHLAESTSP------VQSMLDAYFPEL 317
            |||.:|:.||||||:|||||||.||:.||.:|:|:  |:...:.:||      ||||||||||||
Zfish   243 LPLWNLVLPTVLHGILHYIISSSIQRLVLYLLRRR--NNGSPKHSSPGSGMDTVQSMLDAYFPEL 305

Human   318 IANFAASLCSDVILYPLETVLHRLHIQGTRTIIDNTDLGYEVLPINTQYEGMRDCINTIRQEEGV 382
            :|:||||||:||:|:||||||||||||||||||||||||:|||||||||||||||||.||:|||.
Zfish   306 MASFAASLCADVLLFPLETVLHRLHIQGTRTIIDNTDLGFEVLPINTQYEGMRDCINAIRREEGT 370

Human   383 FGFYKGFGAVIIQYTLHAAVLQITKIIYSTLLQN 416
            .|||||||::::||:|||.||||||:||||||:|
Zfish   371 MGFYKGFGSIVVQYSLHATVLQITKMIYSTLLRN 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A46	NP_620128.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		15/28 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..93		17/48 (35%)
		Solcar 1	96..187		75/90 (83%)
		Solcar 2	311..413		84/101 (83%)
		Mito_carr	317..402	CDD:395101	69/84 (82%)
slc25a46	NP_001002558.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..77		41/93 (44%)
		Solcar 1	80..171		75/90 (83%)
		Solcar 2	299..401		84/101 (83%)
		Mito_carr	305..390	CDD:395101	69/84 (82%)