DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FCGR2C and zgc:154125

DIOPT Version :9

Sequence 1:	NP_963857.3	Gene:	FCGR2C / 9103	HGNCID:	15626	Length:	323	Species:	Homo sapiens
Sequence 2:	XP_005170695.1	Gene:	zgc:154125 / 768188	ZFINID:	ZDB-GENE-061013-717	Length:	426	Species:	Danio rerio

Alignment Length:	279	Identity:	70/279 - (25%)
Similarity:	103/279 - (36%)	Gaps:	74/279 - (26%)

- Green bases have known domain annotations that are detailed below.

Human    49 KAVLKLEPQWINVLQEDSVTLTCRGTHSPESDSIPWFHNGNLIPTHTQPSYRFKANNNDSGEYTC 113
            |.|:.|.|::..|...|.|||.|:|..:|..    |..||...|.............:::|:|.|
Zfish    21 KPVVSLRPRFPQVYVGDDVTLICKGGSNPTK----WVINGIEQPHQNDVMLLTTVTPHNNGQYEC 81

Human   114 -QTGQTSLSDPVHLTVL-SEWLVLQTPH-----LEFQEGETIVLR------CHSWKDKPLVKVTF 165
             |.|:.  ||||.|||| .|.|...:|.     :...||..:||:      .|:||       .|
Zfish    82 EQNGEK--SDPVPLTVLVLEALAQLSPSVGGSVISKGEGRNLVLQVDDAEELHNWK-------CF 137

Human   166 FQNGKSK-KFSRSDPNFSIPQA------NHSHSGDYHCTGNIGYTLYSSKPVTITVQ------AP 217
            ...||.: |..|.|.|..:.:|      ..:....:.|...  ...:.|..||:.:.      .|
Zfish   138 AFRGKREFKLDRIDVNKKLKRAVIFAELKDAERATFWCLNK--NATHRSNAVTLKITDKLVMLEP 200

Human   218 SSSPMGIIVAVVTGIAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQPEE 282
            .::|              |::...|||      |..|...:.|:.|.|.   :..|.|    |:.
Zfish   201 PAAP--------------ALLGDSVAL------RCVAWGAEKVEKATFY---KNQIEI----PDI 238

Human   283 TNNDYETADGGYMTLNPRA 301
            |.:.|.      :|..|.|
Zfish   239 TADTYN------ITATPEA 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FCGR2C	NP_963857.3	Ig1_FcgammaR_like	50..128	CDD:143229	25/78 (32%)
		IG_like	56..128	CDD:214653	23/72 (32%)
		Ig2_FcgammaR_like	132..214	CDD:143230	21/99 (21%)
		IG_like	138..214	CDD:214653	20/93 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	277..323		6/25 (24%)
zgc:154125	XP_005170695.1	Ig	22..95	CDD:299845	25/78 (32%)
		IG_like	33..95	CDD:214653	22/67 (33%)
		Ig	197..269	CDD:299845	19/88 (22%)
		IG_like	200..270	CDD:214653	19/85 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I12521
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.960