DRSC/TRiP Functional Genomics Resources

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Protein Alignment KIFC2 and kif13b

DIOPT Version :9

Sequence 1:NP_665697.1 Gene:KIFC2 / 90990 HGNCID:29530 Length:838 Species:Homo sapiens
Sequence 2:XP_031758942.1 Gene:kif13b / 100492799 XenbaseID:XB-GENE-956968 Length:1943 Species:Xenopus tropicalis


Alignment Length:345 Identity:123/345 - (35%)
Similarity:168/345 - (48%) Gaps:59/345 - (17%)


- Green bases have known domain annotations that are detailed below.


Human   410 IRVLCRLRPGT-------SSSLVSVE-------PGPGGTVTTCYRGRHRRFRLDWVF-PPDASQE 459
            ::|..|:||..       :..:|.||       |..........|.:.:.|..|..| ..|.|.:
 Frog     6 VKVAVRIRPMNRREVDLQTKCVVDVENNQIVLYPSNASLSKGDARSQPKVFAYDHCFWSMDESVK 70

Human   460 EVFRELEPAVLSCL---------RGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQSLF-RE 514
            |.|.. :..|..||         .||:.|||.|||||:||:|:|.|..:.||::||...:|| |.
 Frog    71 EKFAG-QDVVFQCLGENILQNAFEGYNACIFAYGQTGSGKSYTMMGTADQPGLIPRLCSTLFERT 134

Human   515 MGAGRQH---RVTLSMVEIYNEAVRDLLAP-GPPERLAVRQ----GPEGQGGIQVAGLTHWDVPN 571
            ..|..:.   :|.:|.:|||||.|||||.| |..:.|.||:    ||      .|.||:...|.:
 Frog   135 QKAENEELSFKVEVSFMEIYNEKVRDLLDPKGSRQSLKVREHKVLGP------YVDGLSKLAVTS 193

Human   572 LETLHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAG----TLHLVDLAGSE 632
            .:.:..::..|..:|..|||.||:.||||||:..:.|.........||:|    .|.||||||||
 Frog   194 YKDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIILTHTLVDVKSGTSGEKVSKLSLVDLAGSE 258

Human   633 RARKAGAAGPPRGDPDGARRLREAQTINRSLLALGGVMAAL------RAHRPHVPFRDSQLTRLL 691
            ||.|.||||         .||:|...||:||..||.|::||      :.....||:|||.||.||
 Frog   259 RATKTGAAG---------ERLKEGSNINKSLTTLGLVISALADQGAGKNKNKFVPYRDSVLTWLL 314

Human   692 QPALGPGTTAVLLLQVGAGA 711
            :.:||..:...::..|...|
 Frog   315 KDSLGGNSKTAMVATVSPAA 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KIFC2NP_665697.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..48
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..185
Motor_domain 407..707 CDD:277568 121/339 (36%)
KISc 409..707 CDD:214526 121/339 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 718..792
kif13bXP_031758942.1 KISc_KIF1A_KIF1B 4..360 CDD:276816 123/345 (36%)
Kinesin_assoc 357..469 CDD:406567
FHA 449..544 CDD:238017
KIF1B 755..801 CDD:403579
DUF3585 <1097..1141 CDD:419985
DUF3694 <1185..1277 CDD:403614
CAP_GLY 1810..1873 CDD:396049
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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