Protein Alignment KIFC2 and kifc2

DIOPT Version :9

• Sequence 1: NP_665697.1
• Gene: KIFC2 / 90990
• HGNCID: 29530
• Length: 838
• Species: Homo sapiens
• Sequence 2: XP_002941548.2
• Gene: kifc2 / 100485082
• XenbaseID: XB-GENE-995645
• Length: 924
• Species: Xenopus tropicalis
• Alignment Length: 956
• Identity: 312/956 - (32%)
• Similarity: 455/956 - (47%)
• Gaps: 255/956 - (26%)

Human     1 MYAFYSLLIYIFYSLFRRDGGAAAAAE-----PGDPAQRARKPRGRRRPDLPAPELWTELTGLAA 60
            |:||||||:||.|:..||....|...:     |.|||.:.:|    ::|  |..:||.||..|.:
 Frog     1 MFAFYSLLVYIIYTFLRRQQPPAGDIQHQGQLPDDPAGKNKK----KQP--PQAQLWPELDDLES 59

Human    61 SSEPEDGSEGAAE----GRAAAVSLEEALLRLAEFLSVQLGAEESCGGP-ADLGQSGEVPS-LLT 119
            ||:.:..|....|    ..:..:.|::....|.|||:.:  .|.:.|.| |...:|.:.|| ||.
 Frog    60 SSDSDGVSNSETEEDDDPESRCLLLQDVNSPLTEFLAFK--QEAAMGRPSAGPEESAKPPSPLLV 122

Human   120 VTSQLLALL----------------------------AWLRSPRG-------------------- 136
            |.|.|:..|                            ..||:.||
 Frog   123 VMSHLITFLEHYSQMQRLQGKAQEYRNQLRQEERRRRKQLRTLRGAYRQRMRDKLSLIGSLEIVI 187

Human   137 --RQALLQGTQPAP-----RVRPPSPDGSTSQEESPSHFTAVPGE--PLGDETQGQQPLQLEEDQ 192
              :|.:|:..|...     .|.|.||.|.....||   .:.:.||  .|.:|..|.:. .:||.:
 Frog   188 NEQQGMLERLQSGAIGQMLPVSPHSPVGVHKLVES---ISVLQGERAQLREEIGGLKQ-DIEEKE 248

Human   193 RAWQRLEQLILGQLEELKQQLEQQEEELGRLRLGVGATDSEKRVQHLTLENEALKQSLSLMRDLL 257
            |..:.|...:..|:||||.:::|:||||.:||:.:|.||||||:|:|::|||:|||:||:.:.||
 Frog   249 REKETLSCTLQQQIEELKVKIQQREEELSQLRMEMGVTDSEKRIQNLSVENESLKQNLSVTQGLL 313

Human   258 ------------------------------------------------LHWGPGPPIRAPQEEAE 274
                                                            :.|.....||...|:.:
 Frog   314 ERMATVTAQPPAHLMKENEDLRNKVQHLEGSLQQKVEQLVLTKGQVDTMQWCKEEEIRHMDEKIQ 378

Human   275 AL--------------------LE---------------------------------LQGRLQEA 286
            .|                    ||                                 |:.||:|:
 Frog   379 GLQLSLENERKKPPHVEYVTKTLEIESPTMIRSMMEAEERNRVLLSQISCQGEKCQKLEDRLKES 443

Human   287 QDTTEALRAQLGVQEVQLQGLQGALQQ----LQQETEQ------NC-RRELQQMHGQLAGLRARM 340
            :|.|..||.::...|.:::.|:..|.:    |:.:.|:      .| .:.|..:..||||:::|:
 Frog   444 EDLTTNLRVKISSYETEIEKLKHELMEEIHHLESQKEEAIKEASECSEQHLDHLKEQLAGVQSRL 508

Human   341 ASL-------RQGCGDLRGLVSTFTQSCQGSLSEARGQVSWALGALSSGGPG--------TQLPE 390
            |||       :.....||..|..|:|..:.|:.||:.|:..|:..:|.....        .||.:
 Frog   509 ASLQPLLKNMKTNYNSLRSQVKNFSQFYEMSIREAKKQICSAITDVSESNKDLLAKYQREVQLRK 573

Human   391 GQQGPPAGCPGRLPELKGNIRVLCRLRP--------GTSSSLVSVEPGPGGTVTTCYRGRHRRFR 447
            ...       .:|.|||||||||||:||        |:.:|.::::......::..|:|:.:.|.
 Frog   574 RYH-------NQLVELKGNIRVLCRVRPHSHNNEEEGSLTSPITIDMNDDTRLSVFYKGKEKNFE 631

Human   448 LDWVFPPDASQEEVFRELEPAVLSCLRGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQSLF 512
            ||.||.|.|.|||||:|:||.|:||:.||:||||.|||||:||||:|||..|:|||..||:|:|:
 Frog   632 LDKVFVPQAKQEEVFQEIEPMVMSCINGYNVCIFAYGQTGSGKTYTMEGTLENPGINQRAMQALY 696

Human   513 REMGAGR---QHRVTLSMVEIYNEAVRDLLAPGPPERLAVRQGPEGQGGIQVAGLTHWDVPNLET 574
            :||.|.:   .:.|:|||||||||.:||||:..|.|:|.::..|:|.|.:.|.|||..:|.:...
 Frog   697 KEMEARKGLWHYTVSLSMVEIYNEVIRDLLSKDPQEKLDIKLNPDGSGQLHVPGLTSTEVNSFRH 761

Human   575 LHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAGTLHLVDLAGSERARKAGA 639
            :.::|.||:.||||..|.||:||||||||:|:.:..........|.|.|:|||||||||..|:||
 Frog   762 IKKLLTLGKKNRATFCTNMNERSSRSHALLTINISGKDLTTGTVTTGKLNLVDLAGSERVCKSGA 826

Human   640 AGPPRGDPDGARRLREAQTINRSLLALGGVMAALRAHRPHVPFRDSQLTRLLQPALGPGTTAVLL 704
            .|         .||:|||.||:||||||.|:.||||.:.|:|||:|:||.|||.:||.|...|::
 Frog   827 EG---------ERLKEAQNINKSLLALGEVIQALRAKQGHIPFRNSKLTYLLQDSLGKGNKTVMM 882

Human   705 LQVGAGAGQ----VCACRSPPTRARPPAPLARR------SPRGRRI 740
            :||....|.    ||:.:           .|:|      .|..|||
 Frog   883 VQVSPSEGNVGETVCSLK-----------FAQRVCKVELGPASRRI 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIFC2	NP_665697.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..48		7/29 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..185		14/51 (27%)
		Motor_domain	407..707	CDD:277568	154/310 (50%)
		KISc	409..707	CDD:214526	152/308 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	718..792		6/29 (21%)
kifc2	XP_002941548.2	SMC_prok_B	230..>535	CDD:274008	72/305 (24%)
		KISc_C_terminal	583..910	CDD:276817	161/346 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D181609at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920