back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TBX18 and mls-1

DIOPT Version :9

Sequence 1:	NP_001073977.1	Gene:	TBX18 / 9096	HGNCID:	11595	Length:	607	Species:	Homo sapiens
Sequence 2:	NP_498640.1	Gene:	mls-1 / 186741	WormBaseID:	WBGene00003376	Length:	252	Species:	Caenorhabditis elegans

Alignment Length:	191	Identity:	102/191 - (53%)
Similarity:	136/191 - (71%)	Gaps:	12/191 - (6%)

- Green bases have known domain annotations that are detailed below.

Human   140 RVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVPVDNKRYRYVYH 204
            ||.||.:.||:|||.:|||||:||:||||||.:.|.|:||||.:.|.:.:|:..::.||:||.:|
Worm    32 RVFLQSSNLWRRFHNLGTEMIVTKSGRRMFPTLSVIIAGLDPVKSYVVMVDLECIEMKRFRYSFH 96

Human   205 SSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELDDQGHIILHSMHKYQPR 269
            .|||:..|..:|.:|.|:::|.||||.|..|||..:||||:|||||:||:.||||::|||||:||
Worm    97 QSKWISTGPGESELPSRMFVHTDSPARGAHWMRAPVSFDKMKLTNNQLDNNGHIIVNSMHKYRPR 161

Human   270 VHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRD 330
            ||:|.:|            ..:....|||.||.|..||||||.:||.|||:.||||||||:
Worm   162 VHIIEQD------------DSQKRHTFSFEETEFIAVTAYQNHRITSLKIESNPFAKGFRE 210

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.