DRSC/TRiP Functional Genomics Resources

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Protein Alignment ESAM and beat-IIb

DIOPT Version :9

Sequence 1:NP_620411.2 Gene:ESAM / 90952 HGNCID:17474 Length:390 Species:Homo sapiens
Sequence 2:NP_650613.2 Gene:beat-IIb / 42082 FlyBaseID:FBgn0038494 Length:407 Species:Drosophila melanogaster


Alignment Length:214 Identity:39/214 - (18%)
Similarity:68/214 - (31%) Gaps:88/214 - (41%)


- Green bases have known domain annotations that are detailed below.


Human    72 MWFFKQKEKEDQVLSYINGVTTSKPGVSLVYSMPSR--NLSLRLEG------------------- 115
            ||         |.||..:  |:.:...:.|.:.|:.  |.|.:||.                   
  Fly     1 MW---------QTLSTFS--TSLRAAAAAVAAQPAATCNCSCKLENAEMHSHMLPSAEIATTAVR 54

Human   116 -------LQEKDSGPYSCSVNVQDKQGKSRGHSIKTL---------------ELNVLVPPAPPSC 158
                   :...:|..|||:..         .:.|:.|               ::|:||  .||:.
  Fly    55 RCCCRTKITRSNSSNYSCNYG---------SNVIQWLLLLCLFCDFGQAALRDVNLLV--EPPAV 108

Human   159 RLQGVPHVGANVTLSC-----QSP-------RSKPAVQYQWDRQLPSFQTFFAPALDVIRGSLSL 211
            |.      |.:|.|.|     ::|       |.:.........:.|..:.|..|.:.|.....:.
  Fly   109 RR------GQSVALRCDYQLVEAPLYSIKFYRGQMEFYRYTPGEYPPTKVFQFPGIRVDENGSNA 167

Human   212 T-----NLSSSMAGVYVCK 225
            |     |:|..::|.:.|:
  Fly   168 TTVLIRNVSFGLSGQFSCE 186

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ESAMNP_620411.2 V-set 40..150 CDD:311561 19/120 (16%)
IG_like 166..241 CDD:214653 15/77 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 316..368
beat-IIbNP_650613.2 IG_like 108..198 CDD:214653 16/85 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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