Protein Alignment ESAM and igcm-1

DIOPT Version :9

• Sequence 1: NP_620411.2
• Gene: ESAM / 90952
• HGNCID: 17474
• Length: 390
• Species: Homo sapiens
• Sequence 2: NP_508166.1
• Gene: igcm-1 / 180433
• WormBaseID: WBGene00018215
• Length: 1073
• Species: Caenorhabditis elegans
• Alignment Length: 210
• Identity: 45/210 - (21%)
• Similarity: 85/210 - (40%)
• Gaps: 46/210 - (21%)

Human    26 PSRAQLQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQPWEVPFVMWFFKQKEKEDQVLSYING 90
            ||.:.::......:..:|.|.......|...:..::||..:...|       ::...:.|.:..
 Worm   152 PSESVIEGDFMTAKCVSVGGSPQPTFTWTLPNDTIASSAIFTTQF-------RDGATESLLHFR- 208

Human    91 VTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGPYSCSVNVQDKQGKSRGHSIKTLELNVLVPPAP 155
            ||:|..|.|:...:.:|.:   |.|               :.||       :|:.:||||..|..
 Worm   209 VTSSDDGKSVQCDVTNRAM---LGG---------------ETKQ-------VKSSQLNVLYKPVV 248

Human   156 PSCRLQGVPHV----GANVTLSCQSPRSKPAVQYQWDRQLPSFQTFFAPALDVIRGSLSLTNLSS 216
            .....:.:.|:    |..|.|:|.|..:.||..|:| :.:.|.:.:        :|.:....:.|
 Worm   249 FVTPTENLTHLSVEEGELVNLTCNSASNPPAHSYEW-KHIASGERY--------QGKIWPIRVDS 304

Human   217 SMAGVYVCKAHNEVG 231
            ||:|.:.|::.||:|
 Worm   305 SMSGDFECRSTNELG 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ESAM	NP_620411.2	V-set	40..150	CDD:311561	20/109 (18%)
		IG_like	166..241	CDD:214653	19/70 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..368
igcm-1	NP_508166.1	Ig	45..119	CDD:299845
		Ig	146..226	CDD:299845	14/81 (17%)
		Ig_3	245..316	CDD:290638	18/79 (23%)
		IG_like	258..329	CDD:214653	20/71 (28%)
		IG_like	338..398	CDD:214653
		IGc2	347..398	CDD:197706
		Ig_2	429..513	CDD:290606
		IG_like	437..513	CDD:214653
		Ig	537..615	CDD:143165
		IG_like	644..728	CDD:214653
		IGc2	646..719	CDD:197706
		FN3	733..843	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910