Protein Alignment TBX19 and byn

DIOPT Version :9

• Sequence 1: NP_005140.1
• Gene: TBX19 / 9095
• HGNCID: 11596
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_524031.2
• Gene: byn / 39349
• FlyBaseID: FBgn0011723
• Length: 697
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 207/517 - (40%)
• Similarity: 250/517 - (48%)
• Gaps: 155/517 - (29%)

Human    34 GDPTE--KQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPT 96
            |.|.|  :.|:|.|:|..||.||:.:||||||||||||||||:|||.:||||.|||::||:||..
  Fly    78 GSPNELDRNLRISLDDRELWLRFQNLTNEMIVTKNGRRMFPVVKISASGLDPAAMYTVLLEFVQI 142

Human    97 DSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKLNGGGQIMLNS 161
            ||||||||||||||.||.||...:.:|:||:||||||||||.||||:|||||||.||.|||||||
  Fly   143 DSHRWKYVNGEWVPGGKAEVPPSNPIYVHPESPNFGAHWMKEPISFAKVKLTNKTNGNGQIMLNS 207

Human   162 LHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLR 226
            ||||||:||:|||||..|.|....||||||||||||||||:|:||||||||||||||||||
  Fly   208 LHKYEPRVHLVRVGSEQRHVVTYPFPETQFIAVTAYQNEEVTSLKIKYNPFAKAFLDAKER---- 268

Human   227 DVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTH--------------- 276
              |:.:  ..|.|:.   ||:...|.....|..:   .|||.||....:|
  Fly   269 --PDTL--YPHDTHY---GWLIPPPTHYTAAAAA---VAAPPPLSIAQSHGLVASCPSVSSAESV 323

Human   277 -----HGCEHY-------------------------SGLRGHR-----------QAPYPSAYMHR 300
                 ..|:.|                         ||..|..           .||.....:|.
  Fly   324 GPSSGGSCDRYGRSLSSRSVAPTRTTPYSRPRVVSGSGSNGSAGNASSTSPQPPSAPQTPTSLHS 388

Human   301 NHSPSVNLIESSSNNLQVFSGPDS-----------WTSLSSTPHASILSVP--------HTNGPI 346
            ..:.||:...|||:...:.|.|.:           :.|:.::|.||:.|.|        :.|...
  Fly   389 TSTGSVSTSVSSSSGGGIGSAPSTGCFSSSYAQSGFMSVDASPTASVFSYPSSWQSNGNYWNATS 453

Human   347 NPGP---------------SPYPCLWTISNGAGG--PSGPGPEVHASTP---------------- 378
            .|||               ||.|     :||:..  .|.|...:|..||
  Fly   454 VPGPMPMNVCSGRNISSHNSPSP-----TNGSPSYTTSSPSYTIHHLTPHSHQYNMAQTDIYGTG 513

Human   379 -----GAFLLGNPAV--------------TSPPSVLSTQAPTSAGVEVLGEPSLTSIAVSTW 421
                 ||...|:|..              |||...|.|.|       ||..||..|.:.|.|
  Fly   514 VGVGGGAGTTGSPQAAYGAAAHQVYHPTPTSPTHQLYTNA-------VLNAPSALSYSASGW 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX19	NP_005140.1	T-box	43..218	CDD:307177	132/174 (76%)
byn	NP_524031.2	TBOX	86..268	CDD:238106	137/181 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	290	1.000	Domainoid score	I1560
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	322	1.000	Inparanoid score	I2513
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	1	1.000	-	-		FOG0002920
OrthoInspector	1	1.000	-	-		otm41427
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4488
SonicParanoid	1	1.000	-	-		X2738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.960