Protein Alignment TBX19 and Doc2

DIOPT Version :9

• Sequence 1: NP_005140.1
• Gene: TBX19 / 9095
• HGNCID: 11596
• Length: 448
• Species: Homo sapiens
• Sequence 2: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Alignment Length: 433
• Identity: 138/433 - (31%)
• Similarity: 199/433 - (45%)
• Gaps: 90/433 - (20%)

Human    41 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHRWKYVN 105
            :::.|::..||::|.::..|||:||:||||||.:::||:||:..:.|.:||:.||....|:|:..
  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSG 120

Human   106 GEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIMLNSLHKYEPQV 169
            .:|||||..|..|...:|:|||||..||||...||.|:||||||. |:..|.|:|.|:|||:|::
  Fly   121 SQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRL 185

Human   170 HIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHLR---- 226
            |::|.....::    .....|.||:|:|||||||:.||.|||..|||||.|.:..:....|
  Fly   186 HVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSS 250

Human   227 -------DVPEAISESQHVTYSHL-----------GGWIFSNPDG-----------VCTAGNSNY 262
                   |...::|.||..:.|.:           |.....:.||           .|:..:|..
  Fly   251 SPTGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLD 315

Human   263 QYAAP------LPLPAPHTHHGCEHYSGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSG 321
            ..:.|      |..|.||.|          .|.. |:|.    :..|.|...::....|:|....
  Fly   316 DQSVPGASSLALGSPPPHLH----------SHSH-PHPL----QARSASSVFMQHFQQNMQSLLR 365

Human   322 PDSWTSLSST----PHASILSVPHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEVHASTPGAFL 382
            | |...|:.|    ||       ...|.|...|. ||....:..|.|  ..||..:.....||.|
  Fly   366 P-SLVDLACTYFGRPH-------EYGGAIQASPM-YPPAAMLQAGLG--PHPGLNLPPGVSGADL 419

Human   383 LGNPA--------VTSPPSVL--STQAPTSAGVEVLGEPSLTS 415
            :.:.:        |.|..|.|  |||.      :.|.:||..|
  Fly   420 ISDESGAEELELDVGSETSTLEQSTQE------QPLEQPSTRS 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX19	NP_005140.1	T-box	43..218	CDD:307177	85/179 (47%)
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	85/185 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810