Protein Alignment TBX19 and tbx19

DIOPT Version :9

• Sequence 1: NP_005140.1
• Gene: TBX19 / 9095
• HGNCID: 11596
• Length: 448
• Species: Homo sapiens
• Sequence 2: XP_003198807.1
• Gene: tbx19 / 100538180
• ZFINID: ZDB-GENE-110411-5
• Length: 436
• Species: Danio rerio
• Alignment Length: 430
• Identity: 266/430 - (61%)
• Similarity: 313/430 - (72%)
• Gaps: 19/430 - (4%)

Human     9 RKPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPV 73
            |..:|..::.||:||||||||||||||||||||::.||||.||::||||||||||||||||||||
Zfish    17 RGGNDCCITRLLSVVESELQAGREKGDPTEKQLKVSLEDAELWRKFKEVTNEMIVTKNGRRMFPV 81

Human    74 LKISVTGLDPNAMYSLLLDFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKA 138
            ||:||||||||||||.||||.|.|.|||||||||||||||||..|||||||||||||||||||||
Zfish    82 LKVSVTGLDPNAMYSFLLDFTPADGHRWKYVNGEWVPAGKPEPHSHSCVYIHPDSPNFGAHWMKA 146

Human   139 PISFSKVKLTNKLNGGGQIMLNSLHKYEPQVHIVRVGSAHRMVTNCSFPETQFIAVTAYQNEEIT 203
            |:||:|||||||||||||||||||||||||:||||||.:||||||.||.:|||||||||||||||
Zfish   147 PVSFNKVKLTNKLNGGGQIMLNSLHKYEPQIHIVRVGGSHRMVTNISFTDTQFIAVTAYQNEEIT 211

Human   204 ALKIKYNPFAKAFLDAKERNHLRDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPL 268
            |||||:|||||||||||||:|.::..|...|:||:...|. ||..||||.:|:|...|:.|...|
Zfish   212 ALKIKHNPFAKAFLDAKERSHPKNHLEPPVENQHMGIPHC-GWFISNPDSLCSASGGNFPYPGGL 275

Human   269 PLPAPHTHHGCEHYSGLRGHRQAPYPSAYM----HRNHSPSVNLIESSSNNLQVFSGPDSWTSLS 329
            ||  .|.|||.:||..|.|||.|||||.|:    ||.|: :|:|.::.|..:|:|||.:|||.:|
Zfish   276 PL--THHHHGYKHYPSLHGHRAAPYPSPYLPRHHHRGHN-TVSLSDNLSPGVQMFSGHESWTGVS 337

Human   330 STPHASILSV-PHTNGPINPGPSPYPCLWTISNGAGGPSGPGPEV---HASTPGAFLLGNPAVTS 390
            ....|::||: |..|.|  ...|.||||||:|:.....|.||..|   |.....|.  |.....|
Zfish   338 PPGPAAMLSMQPAPNSP--GASSQYPCLWTVSSCTVSSSPPGGVVSLTHGQDEPAD--GASTSAS 398

Human   391 PPSVLSTQAPTSAGVEVLGEPSLTS-IAVSTWTAVASHPF 429
            |.|:|....||.:...|  :|:..| :...:|.:|.:|.|
Zfish   399 PCSLLQAHGPTGSDGSV--DPANHSRVGGMSWASVTTHSF 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TBX19	NP_005140.1	T-box	43..218	CDD:307177	153/174 (88%)
tbx19	XP_003198807.1	TBOX	48..230	CDD:238106	159/181 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194342966
Domainoid	1	1.000	333	1.000	Domainoid score	I6367
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3779
Inparanoid	1	1.050	510	1.000	Inparanoid score	I6368
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG41562
OrthoDB	1	1.010	-	-		D1201455at2759
OrthoFinder	1	1.000	-	-		FOG0002920
OrthoInspector	1	1.000	-	-		otm28332
orthoMCL	1	0.900	-	-		OOG6_119391
Panther	1	1.100	-	-	LDO	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	16	16.270