DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDY1 and Su(var)205

DIOPT Version :9

Sequence 1:	NP_004671.1	Gene:	CDY1 / 9085	HGNCID:	1809	Length:	554	Species:	Homo sapiens
Sequence 2:	NP_476755.1	Gene:	Su(var)205 / 34119	FlyBaseID:	FBgn0003607	Length:	206	Species:	Drosophila melanogaster

Alignment Length:	139	Identity:	37/139 - (26%)
Similarity:	65/139 - (46%)	Gaps:	27/139 - (19%)

- Green bases have known domain annotations that are detailed below.

Human     4 QEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDF--NRRQTEK---QK 63
            :|:.||.|:|:|..| |..:|.::||||.:.::|||||.:| :|:..:..:  :|:..||   .|
  Fly    22 EEYAVEKIIDRRVRK-GKVEYYLKWKGYPETENTWEPENNL-DCQDLIQQYEASRKDEEKSAASK 84

Human    64 KLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKN-------------------- 108
            |...:::::......|..:|.||.:......|..|..:|..|:.:
  Fly    85 KDRPSSSAKAKETQGRASSSTSTASKRKSEEPTAPSGNKSKRTTDAEQDTIPVSGSTGFDRGLEA 149

Human   109 RKLFAASKN 117
            .|:..||.|
  Fly   150 EKILGASDN 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDY1	NP_004671.1	CHROMO	5..58	CDD:214605	21/54 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..106		7/29 (24%)
		crotonase-like	286..482	CDD:119339
Su(var)205	NP_476755.1	CHROMO	24..72	CDD:237991	19/49 (39%)
Su(var)205	NP_476755.1	ChSh	141..202	CDD:197638	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910