DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CDY1 and HP1b

DIOPT Version :9

Sequence 1:	NP_004671.1	Gene:	CDY1 / 9085	HGNCID:	1809	Length:	554	Species:	Homo sapiens
Sequence 2:	NP_001162713.1	Gene:	HP1b / 31834	FlyBaseID:	FBgn0030082	Length:	240	Species:	Drosophila melanogaster

Alignment Length:	271	Identity:	65/271 - (23%)
Similarity:	106/271 - (39%)	Gaps:	75/271 - (27%)

- Green bases have known domain annotations that are detailed below.

Human     5 EFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDF------NRRQTEKQK 63
            ||.||.:.||| ..||.|:|.::||||.:.::||||.::| :|...:.:|      |:::|:|:
  Fly     3 EFSVERVEDKR-TVNGRTEYYLKWKGYPRSENTWEPVENL-DCPDLIANFEESLKNNKKETKKR- 64

Human    64 KLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNRKLFAASKNVRRKAASILSD 128
                      .|.::...:.||.:.::.::..:          :.:||....:.:  :|:.||.
  Fly    65 ----------LSTSSTPESIRSKRKSFLEDDTE----------EQKKLIGFERGL--EASKILG- 106

Human   129 TKNMEIINSTIETLAPDSPFDHKTVSGFQKLEKLDPIAADQQDT----VVFKVTEGKLLRDPLSR 189
                          |.||......:..::..:..|.:.|...:|    ||.:..|.:|.....|.
  Fly   107 --------------ATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTWHTGSG 157

Human   190 PGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQ 254
            .|...|...|......|     |||..|.| |..|..|.|         |||          ||.
  Fly   158 NGNGNTNSVNLGSSGGL-----GSVGGSGA-GDDTAPGSV---------GTT----------GGG 197

Human   255 RNITDDSRDQP 265
            .||.....:.|
  Fly   198 SNIDGGDEEDP 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDY1	NP_004671.1	CHROMO	5..58	CDD:214605	23/58 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	76..106		2/29 (7%)
		crotonase-like	286..482	CDD:119339
HP1b	NP_001162713.1	CHROMO	3..52	CDD:214605	22/50 (44%)
HP1b	NP_001162713.1	Chromo_shadow	100..151	CDD:279701	12/65 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910