Protein Alignment PYGO2 and SNF2

DIOPT Version :10

• Sequence 1: NP_612157.1
• Gene: PYGO2 / 90780
• HGNCID: 30257
• Length: 406
• Species: Homo sapiens
• Sequence 2: NP_014933.3
• Gene: SNF2 / 854465
• SGDID: S000005816
• Length: 1703
• Species: Saccharomyces cerevisiae
• Alignment Length: 216
• Identity: 49/216 - (22%)
• Similarity: 74/216 - (34%)
• Gaps: 39/216 - (18%)

Human    29 RKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPPTPMVDHLVASNPFEDDFGAPKVGVAAPP 93
            ::||.:|.|.........::.....|.||::..|.|      ||..:....   |......:|..
Yeast    59 QQQGISGSQQNIVPNSSDQAELPNNASSHISASASP------HLAPNMQLN---GNETFSTSAHQ 114

Human    94 FLGSPVPFGGFRVQGGMAGQVPPGYSTGGGGGPQPLRR------QPPPFPPNPMGPAFNMPPQGP 152
               ||:          |..|:|  .::.||....|.|:      ....|.|.|.....| ..:.|
Yeast   115 ---SPI----------MQTQMP--LNSNGGNNMLPQRQSSVGSLNATNFSPTPANNGEN-AAEKP 163

Human   153 GYPPPGNMNFPS---QPFNQPLGQNFSPPSGQMMPGPVGGFGPMISPTMGQPPRAELGPPSLSQR 214
            ......|:|..:   ||.|:.| |..:.....:|||.... .||  |...|..:|:.......|.
Yeast   164 DNSNHNNLNLNNSELQPQNRSL-QEHNIQDSNVMPGSQIN-SPM--PQQAQMQQAQFQAQQAQQA 224

Human   215 FAQPGAPFGPSPLQRPGQGLP 235
            .....|....:.||: |:.||
Yeast   225 QQAQQAQQAQARLQQ-GRRLP 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PYGO2	NP_612157.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		10/43 (23%)
		Nuclear localization signal. /evidence=ECO:0000255	41..47		0/5 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..323		34/139 (24%)
		PHD_PYGO2	329..382	CDD:277106
SNF2	NP_014933.3	QLQ	248..281	CDD:462622
		HSA	<617..656	CDD:462194
		PLN03142	650..>1297	CDD:215601
		SnAC	1303..1369	CDD:464219
		Bromo_SNF2	1550..1652	CDD:99950