Protein Alignment PYGO2 and Pygo2

DIOPT Version :10

• Sequence 1: NP_612157.1
• Gene: PYGO2 / 90780
• HGNCID: 30257
• Length: 406
• Species: Homo sapiens
• Sequence 2: NP_001280697.1
• Gene: Pygo2 / 68911
• MGIID: 1916161
• Length: 405
• Species: Mus musculus
• Alignment Length: 406
• Identity: 392/406 - (96%)
• Similarity: 394/406 - (97%)
• Gaps: 1/406 - (0%)

Human     1 MAASAPPPPDKLEGGGGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPP 65
            |||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAASAPPPPDKLEGGSGPAPPPAPPSTGRKQGKAGLQMKSPEKKRRKSNTQGPAYSHLTEFAPPP 65

Human    66 TPMVDHLVASNPFEDDFGAPKVGVAAPPFLGSPVPFGGFRVQGGMAGQVPPGYSTGGGGGPQPLR 130
            |||||||||||||||||||||||.|.|||||||||||||||||||||||||||.|||||||||||
Mouse    66 TPMVDHLVASNPFEDDFGAPKVGGAGPPFLGSPVPFGGFRVQGGMAGQVPPGYGTGGGGGPQPLR 130

Human   131 RQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQPLGQNFSPPSGQMMPGPVGGFGPMIS 195
            |||||||||||||||||||||||||||||||||||||||.||||||||.||:|||||||||||||
Mouse   131 RQPPPFPPNPMGPAFNMPPQGPGYPPPGNMNFPSQPFNQSLGQNFSPPGGQVMPGPVGGFGPMIS 195

Human   196 PTMGQPPRAELGPPSLSQRFAQPGAPFGPSPLQRPGQGLPSLPPNTSPFPGPDPGFPGPGGEDGG 260
            ||||||||.|||||.|.|||.||||||||| ||||||||||||||||||||||||||||||||||
Mouse   196 PTMGQPPRGELGPPPLPQRFTQPGAPFGPS-LQRPGQGLPSLPPNTSPFPGPDPGFPGPGGEDGG 259

Human   261 KPLNPPASTAFPQEPHSGSPAAAVNGNQPSFPPNSSGRGGGTPDANSLAPPGKAGGGSGPQPPPG 325
            |||||||.|||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
Mouse   260 KPLNPPAPTAFPQEPHSGSPAAAVNGNQPSFPPSSSGRGGGTPDANSLAPPGKAGGGSGPQPPPG 324

Human   326 LVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQS 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   325 LVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASAVWACDLCLKTKEIQS 389

Human   391 VYIREGMGQLVAANDG 406
            ||||||||||||||||
Mouse   390 VYIREGMGQLVAANDG 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PYGO2	NP_612157.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..73		70/71 (99%)
		Nuclear localization signal. /evidence=ECO:0000255	41..47		5/5 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..323		205/216 (95%)
		PHD_PYGO2	329..382	CDD:277106	52/52 (100%)
Pygo2	NP_001280697.1	PHD_PYGO2	328..381	CDD:277106	52/52 (100%)