DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SLC7A7 and CG1607

DIOPT Version :9

Sequence 1:	NP_001119577.1	Gene:	SLC7A7 / 9056	HGNCID:	11065	Length:	511	Species:	Homo sapiens
Sequence 2:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	222/468 - (47%)
Similarity:	332/468 - (70%)	Gaps:	4/468 - (0%)

- Green bases have known domain annotations that are detailed below.

Human    21 GDGASPGPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSASFGLSLVIWAVGGLFSVF 85
            |||...|..:|.||.::|||||..:|||::|||||||||.|||:|:.|..|:|::|.:.||||:.
  Fly    33 GDGGGDGGGEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMV 97

Human    86 GALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAIIAITFANYMVQPLFPS 150
            ||.|||||||.|.||||.||||:|.||.|:||||||...:|:.|.||||:|:||:.|:::|.||.
  Fly    98 GAYCYAELGTMITKSGADYAYIMETFGPFMAFIRLWIECMIVRPCSQAIVALTFSTYVLKPFFPE 162

Human   151 CFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALIAVIVAGIVRLGQGASTHFE 215
            |..|..::||||..||.:||.|||..|||.|.|||||||||:|||..:|..|:.:|..|.:.:|
  Fly   163 CTPPEDSARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLALFIIIATGVYQLYLGNTQYF- 226

Human   216 NSFEGSSFAVGDIALALYSALFSYSGWDTLNYVTEEIKNPERNLPLSIGISMPIVTIIYILTNVA 280
             :||.:...|..|||:.||.||:|:||:.||::.||:|:|.:|||.:|.||..:|||:|::.||:
  Fly   227 -TFENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELKDPVKNLPRAIAISCTLVTIVYVMANVS 290

Human   281 YYTVLDMRDILASDAVAVTFADQIFGIFNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLP 345
            :||:|...:::.|.|||||:|::.||:..|.||:.||||.||.:|..::.:||||:.|:..|.:|
  Fly   291 FYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVALSTFGAVNGILLTSSRLFYAGANNGQMP 355

Human   346 DAICMIHVERFTPVPSLLFNGIMALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDR 410
            :.:.||.::||||.|::|...:::::||.|.|||.||||..|:.|..:|::::...:|||.:|:.
  Fly   356 EILTMIQIQRFTPTPAVLAMALLSMLYLTVSDIFALINYVGFATWLSIGVAVLCLPWLRWAQPNL 420

Human   411 PRPLKLSVFFPIVFCLCTIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRI 475
            |||:::.:.||||:.:.|||:..||:|:..:.:..||.:.||.:|.|  ::.:....:|::.::.
  Fly   421 PRPIRVPMVFPIVYLIATIFVTVVPMYASPVETGYGILMILSSIPVY--LVFIAWKNKPIWFQKT 483

Human   476 VGSATRYLQVLCM 488
            :.|.||:||.:.|
  Fly   484 MVSLTRFLQKMLM 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A7	NP_001119577.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..28		3/6 (50%)
SLC7A7	NP_001119577.1	2A0308	20..493	CDD:273332	222/468 (47%)
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	218/459 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157242
Domainoid	1	1.000	455	1.000	Domainoid score	I503
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	1	1.000	-	-		otm41131
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.790