Protein Alignment UBE2M and Ubc2

DIOPT Version :10

• Sequence 1: NP_003960.1
• Gene: UBE2M / 9040
• HGNCID: 12491
• Length: 183
• Species: Homo sapiens
• Sequence 2: NP_477137.1
• Gene: Ubc2 / 34487
• FlyBaseID: FBgn0015320
• Length: 232
• Species: Drosophila melanogaster
• Alignment Length: 162
• Identity: 51/162 - (31%)
• Similarity: 76/162 - (46%)
• Gaps: 27/162 - (16%)

Human    18 GGTKGS------------------SKKASAAQLRIQKDINELNL--PKTCDISFSDP--DDLLNF 60
            ||..||                  |:....:..||||::.|:.|  |..|.   :.|  |:|..:
  Fly    57 GGASGSNAGGGDEPRKEAKTTPRISRALGTSAKRIQKELAEITLDPPPNCS---AGPKGDNLYEW 118

Human    61 -KLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLT 124
             ..::.|....|:.|.|.........||..||||...|.:||.||:.:|.:||:||:::|.|.||
  Fly   119 VSTILGPPGSVYEGGVFFLDIHFSPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALT 183

Human   125 INSIIYGLQYLFLEPNPEDPL-NKEAAEVLQN 155
            |:.::..:..|..:.||.||| ...|.:.|||
  Fly   184 ISKVLLSICSLLTDCNPADPLVGSIATQYLQN 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UBE2M	NP_003960.1	Interaction with UBA3	1..57		15/60 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		5/28 (18%)
		UBCc_UBE2F_UBE2M	29..166	CDD:467414	46/133 (35%)
Ubc2	NP_477137.1	PHA03247	<4..158	CDD:223021	27/103 (26%)
		UBCc_UBE2E	89..229	CDD:467413	46/130 (35%)