DRSC/TRiP Functional Genomics Resources

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Protein Alignment UBE2M and CG5440

DIOPT Version :10

Sequence 1:NP_003960.1 Gene:UBE2M / 9040 HGNCID:12491 Length:183 Species:Homo sapiens
Sequence 2:NP_608594.2 Gene:CG5440 / 33318 FlyBaseID:FBgn0031331 Length:169 Species:Drosophila melanogaster


Alignment Length:142 Identity:51/142 - (35%)
Similarity:75/142 - (52%) Gaps:6/142 - (4%)


- Green bases have known domain annotations that are detailed below.


Human    19 GTKGSSKKAS-AAQLRIQKDINEL--NLPKTCDISFSDPDDLLNF-KLVICPDEGFYKSGKFVFS 79
            ||...|...| :|..||||:::|:  :.|:.|.....: |:|..: ..:|.|.:..|::|.|...
  Fly    10 GTPSCSWTCSNSAVKRIQKELDEITRDPPQYCSAGPKE-DNLYEWTSTIIGPADSVYENGIFKLD 73

Human    80 FKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDP 144
            ......||..||.|...|.:||.||...|.:||:||:|.|.|.|||:.|:..:..|..:.||:||
  Fly    74 IFFPVEYPFAPPVVIFRTPIYHCNIHRLGFICLDILKEKWSPALTISKILLSICSLLTDCNPKDP 138

Human   145 L-NKEAAEVLQN 155
            | .|...|.|:|
  Fly   139 LMAKIGTEYLKN 150

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UBE2MNP_003960.1 Interaction with UBA3 1..57 13/40 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..29 4/10 (40%)
UBCc_UBE2F_UBE2M 29..166 CDD:467414 47/131 (36%)
CG5440NP_608594.2 UBCc_UBE2E 24..164 CDD:467413 46/128 (36%)

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