DRSC/TRiP Functional Genomics Resources

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Protein Alignment UBE2M and CG2574

DIOPT Version :10

Sequence 1:NP_003960.1 Gene:UBE2M / 9040 HGNCID:12491 Length:183 Species:Homo sapiens
Sequence 2:NP_572796.1 Gene:CG2574 / 32190 FlyBaseID:FBgn0030386 Length:239 Species:Drosophila melanogaster


Alignment Length:154 Identity:49/154 - (31%)
Similarity:77/154 - (50%) Gaps:10/154 - (6%)


- Green bases have known domain annotations that are detailed below.


Human    14 EESAGGTKGS-SKKASAAQL-----RIQKDINEL--NLPKTCDISFSDPDDLLNFKL-VICPDEG 69
            ||:|..|..| |.|::.|.|     ||:.::.::  |.|..|...... .|||::.. |..|...
  Fly    41 EETAPSTSHSASGKSTEAPLTGCVVRIKSELQDIRKNPPPNCTADLHH-GDLLHWTAGVNGPVGS 104

Human    70 FYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQY 134
            .|:.|.|....:....||...|:::..|.:||.|:|..|.:||::|.|.|.||:.:..::..:..
  Fly   105 VYEGGHFRLDIRFPASYPFRAPRIRFTTRIYHCNVDSRGAICLDVLGERWSPVMNVAKVLLSIYV 169

Human   135 LFLEPNPEDPLNKEAAEVLQNNRR 158
            |..|.||:|||....|:..:.|||
  Fly   170 LMSECNPDDPLVMCIADQYKTNRR 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UBE2MNP_003960.1 Interaction with UBA3 1..57 14/50 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..29 7/15 (47%)
UBCc_UBE2F_UBE2M 29..166 CDD:467414 42/138 (30%)
CG2574NP_572796.1 UBCc_UEV 66..204 CDD:483950 40/129 (31%)

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