DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SAMD1 and swsn-1

DIOPT Version :9

Sequence 1:	NP_612361.1	Gene:	SAMD1 / 90378	HGNCID:	17958	Length:	538	Species:	Homo sapiens
Sequence 2:	NP_001256907.1	Gene:	swsn-1 / 180324	WormBaseID:	WBGene00004203	Length:	792	Species:	Caenorhabditis elegans

Alignment Length:	358	Identity:	98/358 - (27%)
Similarity:	125/358 - (34%)	Gaps:	124/358 - (34%)

- Green bases have known domain annotations that are detailed below.

Human    13 AAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPE----RTRAEL 73
            ||||:..|||:..|  .|..:.....|.||.::.....::::  .::.||..|.|    :.|..|
Worm   448 AAAASCLAAAAVKA--KHLAQIEERRIKSLVAQLVETQMKKL--EMKLRHFDELEQIMDKERESL 508

Human    74 E----KLIQQRAVLRVSYKGSISY-RNAARVQPPRR----GATPPAPPRA------PRGAP---- 119
            |    :||.:|....:.   .:.| .|.|:.:...|    ||.|...|..      |:..|
Worm   509 EYQRHQLILERQAFHMD---QLKYLENRAKHEAHSRMTSSGALPAGLPPGFEVTGPPQPTPQVQI 570

Human   120 --------------AAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSP-----GPA 165
                          .||.||.||.||..|..|...||.||.:||:    |..|||..     ||.
Worm   571 SAQEAAIPEKMDTSEAATAARPPSTPQAPQAPPVQAAPAPVQAPQ----APQAPPQAYQGYGGPG 631

Human   166 QPGPRAQRAAPLAAPPPAPAAPPA---------------VAPPAGPRRAPPPAVAAREPPLPPPP 215
            .|..:|.|..|......:|..||.               ..||.|.:..|||....:....||||
Worm   632 GPPQQAYRYPPQQGQQYSPYPPPQQQQQHQAQQAQSQAHYGPPGGGQGPPPPPQGQQYYGGPPPP 696

Human   216 ---------------------QP---PAPPQQQQ----PPPPQP-------------QPPPEGGA 239
                                 ||   |.|||||:    ||||||             .|||..|.
Worm   697 GQPYGPPGGYPPQQQRPPYQAQPYPGPPPPQQQRGYGYPPPPQPVFSGHPYQQPYGQMPPPPHGQ 761

Human   240 V----RAGGAARPVSLREVVRYLGG--SGGAGG 266
            .    :.||...|.         ||  .||.||
Worm   762 YQPQQQQGGPMGPP---------GGHHEGGDGG 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SAMD1	NP_612361.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30		8/16 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	92..247		69/248 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..458
		SAM_Atherin-like	459..527	CDD:188982
		SAM	459..525	CDD:197735
swsn-1	NP_001256907.1	RSC8	33..509	CDD:227584	17/64 (27%)
swsn-1	NP_001256907.1	SWIRM-assoc_3	354..415	CDD:374581
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000