Protein Alignment RHBDL1 and rom-1

DIOPT Version :9

• Sequence 1: XP_024306253.1
• Gene: RHBDL1 / 9028
• HGNCID: 10007
• Length: 526
• Species: Homo sapiens
• Sequence 2: NP_498029.2
• Gene: rom-1 / 184989
• WormBaseID: WBGene00004400
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 260
• Identity: 65/260 - (25%)
• Similarity: 107/260 - (41%)
• Gaps: 69/260 - (26%)

Human    88 IGADTFTGLVHSHELPLDPAKLDMLVALAQSNEQGQVCYQELVDLISSKRSSSFKRAIANGQRAL 152
            |...|....:.:.::||...::.   |:.::.:       ||||:...::..:.|.|    ||:
 Worm    27 IPMSTLASRIETRKIPLTNGQIH---AIKEAPD-------ELVDIDGFQKIVTSKAA----QRS- 76

Human   153 PRDGPLDEPGLGVYKRFVRYVAYEIL--PCEVDRRWYFYRHRSCPPPVFMASVTLAQIIVFLCY- 214
                        ..||.:..:|..|:  ..:::...|...:..||||:||..:|:.|:.:|..|
 Worm    77 ------------TIKRIMYDMADPIMSDSQKIEVHSYIDSYSWCPPPIFMLLITIIQVGIFFFYW 129

Human   215 ---GARLNKWV----LQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIG 272
               |.| :.|.    ...:|........::.|..|..||||.:|||:|.||..|..|.::||::|
 Worm   130 ESDGGR-SIWTDCAGCFVHHNHTAPGIFIFAPKLRGEAWRFTSYMFLHAGLNHLLGNVIIQLLVG 193

Human   273 VPLEMVHGLLRISLLYLAGVLAG----------------EAGA---------------HPRPLPW 306
            :|||:.|.:.||..:||..|.:|                .||.               |..||.|
 Worm   194 IPLEVAHKIWRIGPIYLLAVTSGSLLQYAIDPNSLLVGASAGVYALIFAHVANVILNWHEMPLRW 258

Human   307  306
             Worm   259  258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHBDL1	XP_024306253.1	Rhomboid	239..>295	CDD:328780	26/55 (47%)
rom-1	NP_498029.2	Rhomboid	160..308	CDD:279958	33/99 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I3202
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1253228at2759
OrthoFinder	1	1.000	-	-		FOG0000995
OrthoInspector	1	1.000	-	-		otm15732
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45840
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2770
SonicParanoid	1	1.000	-	-		X2844
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.960