Protein Alignment FRMD7 and Frmd7

DIOPT Version :10

• Sequence 1: NP_919253.1
• Gene: FRMD7 / 90167
• HGNCID: 8079
• Length: 714
• Species: Homo sapiens
• Sequence 2: NP_001177261.1
• Gene: Frmd7 / 385354
• MGIID: 2686379
• Length: 703
• Species: Mus musculus
• Alignment Length: 714
• Identity: 608/714 - (85%)
• Similarity: 643/714 - (90%)
• Gaps: 11/714 - (1%)

Human     1 MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCSHLNLAEKEYFGLEFCSHSGNNVWLELLKPITK 65
            ||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||
Mouse     1 MLHLKVQFLDDSQKIFVVDQKSSGKALFNLSCGHLNLAEKEYFGLEFCSHSGNNVWLELLKPITK 65

Human    66 QVKNPKEIVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSEL 130
            |||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 QVKNPKEVVFKFMVKFFPVDPGHLREELTRYLFTLQIKKDLALGRLPCSDNCTALMVSHILQSEL 130

Human   131 GDFHEETDRKHLAQTRYLPNQDCLEGKIMHFHQKHIGRSPAESDILLLDIARKLDMYGIRPHPAS 195
            |||||||.||||.||:|||:|..||.|||.|||:|||||||||||||||||||||||||||.|||
Mouse   131 GDFHEETVRKHLVQTQYLPSQASLESKIMQFHQQHIGRSPAESDILLLDIARKLDMYGIRPQPAS 195

Human   196 DGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMAS 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 DGEGMQIHLAVAHMGVLVLRGNTKINTFNWAKIRKLSFKRKHFLIKLHANILVLCKDTLEFTMAS 260

Human   261 RDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGRKGRLKSLPFER 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
Mouse   261 RDACKAFWKTCVEYHAFFRLSEEPKSKPKTLLCSKGSSFRYSGRTQRQLLEYGKKGRLKSLPFER 325

Human   326 KHYPSQYHERQCRSSPDLLSDVSKQVEDLRLAYGGGYYQNVNGVHASEPVLESRRRNSALEVTFA 390
            |.|||||||||||||||:|||||||||||||.||..||:|||||||||.:|:|||||||:|||||
Mouse   326 KQYPSQYHERQCRSSPDILSDVSKQVEDLRLTYGSSYYRNVNGVHASESMLDSRRRNSAVEVTFA 390

Human   391 TELEHSKPEADPTLLHQSQSSSSFPFIYMDPVFNTEPNPNPDPRDIFSERSSLSSFQTSCKFSGN 455
            .|||||||||:.|.||.|||||||.|||.||||||:    |:|.:.|.|||.||||||:.||:.:
Mouse   391 AELEHSKPEAEATSLHPSQSSSSFTFIYADPVFNTD----PEPIEFFEERSPLSSFQTTSKFADS 451

Human   456 HMSIYSGLTSKVRPAKQLTYTDVPYIPCTGQQVGIMPPQVFFYVDKPPQVPRWSPIRAEERTSPH 520
            |       |||..||:|||||||||||||.|:|.||||||||||||||||||.|.|.|||...|.
Mouse   452 H-------TSKASPARQLTYTDVPYIPCTSQKVDIMPPQVFFYVDKPPQVPRRSLIMAEENMRPD 509

Human   521 SYVEPTAMKPAERSPRNIRMKSFQQDLQVLQEAIARTSGRSNINVGLEEEDPNLEDAFVCNIQEQ 585
            |||:.:|:|||:|||||:|:||.|||||.||||:|||||||||||..|||||:|:|||..|:|||
Mouse   510 SYVDHSAIKPAKRSPRNMRIKSLQQDLQELQEAMARTSGRSNINVEPEEEDPHLDDAFAYNLQEQ 574

Human   586 TPKRSQSQSDMKTIRFPFGSEFRPLGPCPALSHKADLFTDMFAEQELPAVLMDQSTAERYVASES 650
            |||||||||||||||||||||||||||||||:.|.|||...|||||.|.||:|||:|||||||||
Mouse   575 TPKRSQSQSDMKTIRFPFGSEFRPLGPCPALTRKTDLFACTFAEQEFPTVLIDQSSAERYVASES 639

Human   651 SDSESEILKPDYYALYGKEIRSPMARIRLSSGSLQLDEEDEDAYFNTPTAEDRTSLKPCNYFLA 714
            |||||||:|||||.||||..:||.||||||||||||:||||...|.||.|||||.|||||||||
Mouse   640 SDSESEIIKPDYYFLYGKGTKSPRARIRLSSGSLQLEEEDETISFATPGAEDRTLLKPCNYFLA 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRMD7	NP_919253.1	FERM_F1_FRMD7	1..86	CDD:340708	82/84 (98%)
		FERM_B-lobe	94..184	CDD:271216	80/89 (90%)
		FERM_C_FARP1-like	179..299	CDD:270014	118/119 (99%)
		FA	294..327	CDD:462582	31/32 (97%)
Frmd7	NP_001177261.1	FERM_F1_FRMD7	1..86	CDD:340708	82/84 (98%)
		FERM_B-lobe	94..184	CDD:271216	80/89 (90%)
		FERM_C_FARP1-like	179..299	CDD:270014	118/119 (99%)
		FA	294..330	CDD:462582	33/35 (94%)