Protein Alignment HS6ST2 and Hs6st

DIOPT Version :10

• Sequence 1: NP_001070656.1
• Gene: HS6ST2 / 90161
• HGNCID: 19133
• Length: 645
• Species: Homo sapiens
• Sequence 2: NP_524409.2
• Gene: Hs6st / 42380
• FlyBaseID: FBgn0038755
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 172/340 - (50%)
• Similarity: 224/340 - (65%)
• Gaps: 50/340 - (14%)

Human   221 FDIKGDDLIVFLHIQKTGGTTFGRHLVRNIQLEQPCECRVGQKKCTCHRPGKRETWLFSRFSTGW 285
            ||:.|.|::|||||||||||:|||||||::.|::||||:..:|:|.|.||.:.|.|||||:||||
  Fly   141 FDMDGHDVMVFLHIQKTGGTSFGRHLVRDLDLKRPCECQRQRKRCYCFRPHRNENWLFSRYSTGW 205

Human   286 SCGLHADWTELTSCVPSVVDGKRDARLRPSRWRIFQILDAASKDKRGSPNTNAGANSPSSTKTRN 350
            .||||||||||||||        |..|                ||      |.|          .
  Fly   206 KCGLHADWTELTSCV--------DVEL----------------DK------NEG----------E 230

Human   351 TSKSGKNFHYITILRDPVSRYLSEWRHVQRGATWKASLHVCDGRPPTSEELPSCYTGDDWSGCPL 415
            |:|  :.:.||::||.|::||:||:|||:||||||.|.|.|.||..|:.|||:||.|.||....|
  Fly   231 TAK--RRYFYISLLRQPIARYMSEYRHVRRGATWKGSRHWCLGRQATAAELPACYKGKDWLDVDL 293

Human   416 KEFMDCPYNLANNRQVRMLSDLTLVGCYNLSVMPEKQRNKVLLESAKSNLKHMAFFGLTEFQRKT 480
            .:|..|..|||.|||.|||:||.||||||.|.||..:|::|:|.|||.||..||:|||||:|:.:
  Fly   294 DQFAGCESNLAANRQTRMLADLALVGCYNKSSMPAHERDRVMLASAKRNLAAMAYFGLTEYQKMS 358

Human   481 QYLFEKTFNMNFISPFTQYNTT-RASSVE-INEEIQKRIEGLNFLDMELYSYAKDLFLQRYQFMR 543
            ||:||:|||:.|..||.|:||| .|::|: :..:.::|||.||.||:|||::||.|..||:
  Fly   359 QYIFEETFNLRFAIPFEQHNTTISATAVQNLRPDQKRRIEKLNSLDIELYAFAKTLLFQRF---- 419

Human   544 QKEHQEARRKRQEQR 558
              ||.:|:....|||
  Fly   420 --EHLKAKDTNFEQR 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HS6ST2	NP_001070656.1	Sulfotransfer_2	225..531	CDD:427369	159/307 (52%)
Hs6st	NP_524409.2	Sulfotransfer_2	144..411	CDD:427369	159/308 (52%)