Protein Alignment SLC25A14 and CG7943

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_651766.1
• Gene: CG7943 / 43574
• FlyBaseID: FBgn0039741
• Length: 332
• Species: Drosophila melanogaster
• Alignment Length: 337
• Identity: 70/337 - (20%)
• Similarity: 120/337 - (35%)
• Gaps: 93/337 - (27%)

Human    38 WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYS 102
            |:.|..|..|:.|....|:|:.....|..:.|..|.:.|.::::             ||:..||.
  Fly    54 WEEFACGCGAAFVNIAVTYPIYKMIFRQMLHGVPITSAFAQLRH-------------EGLGFLYR 105

Human   103 GIAPALLRQASYGTIKIGIYQSLKRLFVE--RLEDETLLINMICGVVSGVISSTIANPTDVLKIR 165
            |:.|.|.::....:|..|::...:|..||  ||.|..  ..::..||:|...| |..|.:  :::
  Fly   106 GMLPPLAQKTISLSIMFGVFDGTRRYLVEDYRLNDYG--AKVLAAVVAGSAES-ILLPFE--RVQ 165

Human   166 MQAQGSLFQ---GSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLEG 227
            .....|.|.   .:...:|..:....|.|.|:|.|               .|..|......:|..
  Fly   166 TLLADSKFHQHFSNTQNAFRYVVSHHGYRELYRGL---------------EPVFWRNGLSNALFF 215

Human   228 VVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRM- 291
            |:  .:.|::.:.....|...|.:..|...::|.:|.|.|.              |::|::..:
  Fly   216 VL--REEASVRLPKRKSVSTRTVQEFIAGAVIGASISTIFY--------------PLNVIKVSLQ 264

Human   292 --MNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFW-------PNWLRLGPWNI-------- 339
              |.||:                     ||.:...|..:       .|:.|..|:|.
  Fly   265 SEMGQRS---------------------EGSWQACKRIYVERDRRIGNFYRGCPFNTGRSFISWG 308

Human   340 IFFITYEQLKRL 351
            |....||.||:|
  Fly   309 IMNTAYENLKKL 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	23/96 (24%)
		Mito_carr	134..254	CDD:395101	22/122 (18%)
		Mito_carr	262..351	CDD:395101	20/106 (19%)
CG7943	NP_651766.1	Mito_carr	54..136	CDD:395101	23/94 (24%)
		Mito_carr	141..229	CDD:395101	19/109 (17%)
		Mito_carr	235..322	CDD:395101	24/121 (20%)