Protein Alignment SLC25A14 and Dic1

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_650279.1
• Gene: Dic1 / 41640
• FlyBaseID: FBgn0027610
• Length: 280
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 83/324 - (25%)
• Similarity: 142/324 - (43%)
• Gaps: 79/324 - (24%)

Human    43 YGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPA 107
            :|||||:.|...|.|:||.|..||.|...:          .:...:.::.:|:|||..|:|::.:
  Fly    12 FGGLASVGAAMVTHPLDLIKVTLQTQQGHL----------SVAQLIPKLAREQGVLVFYNGLSAS 66

Human   108 LLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL 172
            :|||.:|.|.:.|:|::.|:.    :..::....:.....||::...:..|.|::.:|||....|
  Fly    67 VLRQLTYSTARFGVYEAGKKY----VNTDSFGGKVALAGASGLVGGIVGTPADMVNVRMQNDVKL 127

Human   173 -----------FQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLE 226
                       |.|     .:.:|:|||.:.|:                               .
  Fly   128 PPQQRRNYNNAFDG-----LVRVYRQEGFKRLF-------------------------------S 156

Human   227 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRM 291
            |......|..::...::..||.||.:|:.:....|.::|||.:|...|......:.|:||::||.
  Fly   157 GATAATARGILMTIGQIAFYDQTKIYLLATPYFQDNLVTHFTASLVAGTIATTLTQPLDVLKTRS 221

Human   292 MNQRAIVGHVDLYKGTVDGILKMWKHE------GFFALYKGFWPNWLRLGPWNIIFFITYEQLK 349
            ||.:         .|..:|:..:.||.      |||   ||:.|.::||||..||.|:..|||:
  Fly   222 MNAK---------PGEFNGLWDIVKHTAKLGPLGFF---KGYVPAFVRLGPHTIITFVFLEQLR 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	28/89 (31%)
		Mito_carr	134..254	CDD:395101	21/130 (16%)
		Mito_carr	262..351	CDD:395101	32/94 (34%)
Dic1	NP_650279.1	Mito_carr	10..92	CDD:395101	28/93 (30%)
		Mito_carr	89..184	CDD:395101	21/130 (16%)
		Mito_carr	189..278	CDD:395101	33/97 (34%)