Protein Alignment SLC25A14 and GC2

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_731657.2
• Gene: GC2 / 41449
• FlyBaseID: FBgn0037970
• Length: 319
• Species: Drosophila melanogaster
• Alignment Length: 306
• Identity: 68/306 - (22%)
• Similarity: 120/306 - (39%)
• Gaps: 68/306 - (22%)

Human    42 VYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAP 106
            :.||:|.|:.....:|:|:.||||  |.|:|... .|..|..:.....:....||...:|.|.|.
  Fly    25 INGGVAGIIGVACVYPLDMVKTRL--QNQTIGPN-GERMYTSIADCFRKTIASEGYFGMYRGSAV 86

Human   107 ALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINM----ICGVVSGVISSTIANPTDVLKIRMQ 167
            .::.......||:    :....|...|..:..:|.:    :.|.::|:....:..|.::|||:||
  Fly    87 NIVLITPEKAIKL----TANDFFRYHLASDDGVIPLSRATLAGGLAGLFQIVVTTPMELLKIQMQ 147

Human   168 AQGSLFQG-----------SMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPAL-WEAN 220
            ..|.:...           :.:|....:.::.|..||::.:.:..|.. :.:.|...|.: |..:
  Fly   148 DAGRVAAADRAAGREVKTITALGLTKTLLRERGIFGLYKGVGATGVRD-ITFSMVYFPLMAWIND 211

Human   221 AG-----GSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALA 280
            .|     ||.|.|.    ..:::.|             :||||....::|
  Fly   212 QGPRKSDGSGEAVF----YWSLIAG-------------LLSGMTSAFMVT--------------- 244

Human   281 SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKG 326
              |.|||:||:.     ......:||.:|.:.:..|.||..|.:||
  Fly   245 --PFDVVKTRLQ-----ADGEKKFKGIMDCVNRTLKEEGISAFFKG 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	23/90 (26%)
		Mito_carr	134..254	CDD:395101	24/140 (17%)
		Mito_carr	262..351	CDD:395101	16/65 (25%)
GC2	NP_731657.2	Mito_carr	16..106	CDD:395101	22/87 (25%)
		Mito_carr	123..203	CDD:395101	15/80 (19%)
		Mito_carr	228..302	CDD:395101	21/91 (23%)