DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC25A14 and CG2616

DIOPT Version :10

Sequence 1:NP_001269126.1 Gene:SLC25A14 / 9016 HGNCID:10984 Length:353 Species:Homo sapiens
Sequence 2:NP_649731.1 Gene:CG2616 / 40915 FlyBaseID:FBgn0037512 Length:449 Species:Drosophila melanogaster


Alignment Length:367 Identity:75/367 - (20%)
Similarity:136/367 - (37%) Gaps:113/367 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    47 ASIVAEFGTFPVDLTKTRLQVQ------------------------GQSIDARFKEIKYRGMFHA 87
            |.|.|.|.| |:|:.|||:|.|                        |..:.:..:..::...:.|
  Fly   101 AMITACFMT-PLDVIKTRMQSQQSPAHKCFFYSNGLMDHLFASGPNGSELASLRQRPQFSSSWDA 164

Human    88 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDE---------------- 136
            |.:|.:.||:.||:||:.|.|:.......|....|:..|..:::..|..                
  Fly   165 LMKISRHEGLAALWSGLGPTLVSALPSTIIYFVAYEQFKARYLQIYESHYNKSQEPRHLEIRDTK 229

Human   137 ---TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRCLC 198
               ..::.|:.||.:.:.:.|:.:|.::::.:||||...: ..|:.....:...:|..||||   
  Fly   230 KSLPSVVPMMSGVTARICAVTVVSPIELVRTKMQAQRQTY-AQMLQFVRSVVALQGVWGLWR--- 290

Human   199 SKAVTGCVLWLMPVIPALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHL---------- 253
                                        |:.||..|.....|:..|:|:..|::|          
  Fly   291 ----------------------------GLRPTILRDVPFSGIYWPIYESLKQNLGHGSQPSFSL 327

Human   254 -ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLY----------KGT 307
             .|:|:|..|:             .|:.:.|.|||:|   :::...|...::          |.|
  Fly   328 SFLAGVMAGTV-------------AAIVTTPFDVVKT---HEQIEFGERVIFTDSPARDFGKKST 376

Human   308 VDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 349
            ...:..:::..|...|:.|..|..|::.|...|...|:|..|
  Fly   377 FSRLTGIYRTHGVRGLFAGCGPRLLKVAPACAIMISTFEYSK 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC25A14NP_001269126.1 Mito_carr 37..133 CDD:395101 27/109 (25%)
Mito_carr 134..254 CDD:395101 25/149 (17%)
Mito_carr 262..351 CDD:395101 20/98 (20%)
CG2616NP_649731.1 Mito_carr 86..207 CDD:395101 27/106 (25%)
Mito_carr 230..321 CDD:395101 24/122 (20%)
Mito_carr 321..425 CDD:395101 23/114 (20%)

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