Protein Alignment SLC25A14 and Dic4

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_649054.1
• Gene: Dic4 / 40039
• FlyBaseID: FBgn0036808
• Length: 302
• Species: Drosophila melanogaster
• Alignment Length: 318
• Identity: 81/318 - (25%)
• Similarity: 139/318 - (43%)
• Gaps: 65/318 - (20%)

Human    43 YGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPA 107
            :||.||:...|...|:|:.||.:|:|.|.          |.:...:.||...:|.|..|.|.:.|
  Fly    25 FGGFASMCVAFAVAPIDIVKTHMQIQRQK----------RSILGTVKRIHSLKGYLGFYDGFSAA 79

Human   108 LLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIANPTDVLKIRMQAQ--- 169
            :|||.:...|...:|.:.|::  |.::.::.|..:|.|.|:|...|....|||::.:|||..
  Fly    80 ILRQMTSTNIHFIVYDTGKKM--EYVDRDSYLGKIILGCVAGACGSAFGIPTDLINVRMQTDMKE 142

Human   170 --------GSLFQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLE 226
                    ..:|.|     .|.|.::||.:.|::                          |||:
  Fly   143 PPYKRRNYKHVFDG-----LIRIPKEEGWKALYK--------------------------GGSV- 175

Human   227 GVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRM 291
                ...::::....::..|||.|..:..:..:.|.:..||::|....:..:..::|:|||||.|
  Fly   176 ----AVFKSSLSTCSQIAFYDIIKTEVRKNISVNDGLPLHFLTSLGTSIISSAITHPLDVVRTIM 236

Human   292 MNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 349
            ||.|.  |.   ::......:.|.:. |....|:||.|..:|..|...:.|:.||||:
  Fly   237 MNSRP--GE---FRTVFQASVHMMRF-GVMGPYRGFVPTIVRKAPATTLLFVLYEQLR 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	27/89 (30%)
		Mito_carr	134..254	CDD:395101	26/130 (20%)
		Mito_carr	262..351	CDD:395101	27/88 (31%)
Dic4	NP_649054.1	Mito_carr	26..100	CDD:395101	26/83 (31%)
		Mito_carr	104..201	CDD:395101	26/132 (20%)
		Mito_carr	211..292	CDD:395101	27/84 (32%)