Protein Alignment SLC25A14 and SCaMC

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_729802.1
• Gene: SCaMC / 39415
• FlyBaseID: FBgn0052103
• Length: 583
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 90/346 - (26%)
• Similarity: 149/346 - (43%)
• Gaps: 68/346 - (19%)

Human    28 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRIC 92
            |.....:||.|:..|.||:|..|:...|.|:|..|..||||.|.:          |:...:..:.
  Fly   276 TQKEMQTGLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRM----------GISECMHIML 330

Human    93 KEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMI----CGVVSGVISS 153
            .|.|..:::.|....:|:.|.....|...|:.:|||.  |.:|.:..::::    .|..:|.||.
  Fly   331 NEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLI--RGDDGSRQMSIVERFYAGAAAGGISQ 393

Human   154 TIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWE 218
            ||..|.:|||.|:..:.:.....:..:.:.||:|||.|..:|               ..:|
  Fly   394 TIIYPMEVLKTRLALRRTGQYAGIADAAVKIYKQEGVRSFYR---------------GYVP---- 439

Human   219 ANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGAL 279
                 ::.|::|.|       |::|.||:..|:..|.:....:.  ..|:....||    ..|.|
  Fly   440 -----NILGILPYA-------GIDLAVYETLKRRYIANHDNNEQ--PSFLVLLACGSTSSTLGQL 490

Human   280 ASNPVDVVRTRMMNQRA------------IVGHVDLYKG--TVDGIL-KMWKHEGFFALYKGFWP 329
            .|.|:.:||||:..|.|            .:...|.:.|  |:.|:. |:.:.||...||:|..|
  Fly   491 CSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITP 555

Human   330 NWLRLGPWNIIFFITYEQLKR 350
            |:|::.|...|.::.||...|
  Fly   556 NFLKVLPAVSISYVVYEYTSR 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	26/95 (27%)
		Mito_carr	134..254	CDD:395101	28/123 (23%)
		Mito_carr	262..351	CDD:395101	31/108 (29%)
SCaMC	NP_729802.1	FRQ1	114..242	CDD:444056
		PTZ00169	290..559	CDD:240302	80/313 (26%)