Protein Alignment SLC25A14 and PMP34

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_728982.1
• Gene: PMP34 / 38532
• FlyBaseID: FBgn0052250
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 69/352 - (19%)
• Similarity: 142/352 - (40%)
• Gaps: 87/352 - (24%)

Human    29 VSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICK 93
            :|..:|..|:...|.|.....:|....:|:|..::|||:: ::.|.|           :..::.|
  Fly     7 LSQVLSYQNFVHAVSGAAGGCIAMSTFYPLDTVRSRLQLE-EAGDVR-----------STRQVIK 59

Human    94 E----EGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDE-TLLINMICGVVSGVISS 153
            |    ||..:||.|:.|.|........:....:.:||.:.......: :.|.:::.|.::|:|:.
  Fly    60 EIVLGEGFQSLYRGLGPVLQSLCISNFVYFYTFHALKAVASGGSPSQHSALKDLLLGSIAGIINV 124

Human   154 TIANPTDVLKIRMQAQG-------------SLFQGSMIGSFIDIYQQEGTRGLWRCLCSKAVTGC 205
            ....|..|:..|::.:.             :|.:|...     :.::||..|||        :|.
  Fly   125 LTTTPFWVVNTRLRMRNVAGTSDEVNKHYKNLLEGLKY-----VAEKEGIAGLW--------SGT 176

Human   206 VLWLMPVI-PALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLI--LSGMMGDTILTHF 267
            :..||.|. |||                         :..:|::.|::::  ..|.||.  |:.|
  Fly   177 IPSLMLVSNPAL-------------------------QFMMYEMLKRNIMRFTGGEMGS--LSFF 214

Human   268 VSSFTCGLAGALA---SNPVDVVRTRMMNQ--------RAIVGHVDLYKGTVDGILKMWKHEGFF 321
               |...:|.|.|   :.|:.:|:|:..::        ....|.....:.|::.::.:.:|:|..
  Fly   215 ---FIGAIAKAFATVLTYPLQLVQTKQRHRSKESDSKPSTSAGSTPRTESTLELMISILQHQGIR 276

Human   322 ALYKGFWPNWLRLGPWNIIFFITYEQL 348
            .|::|.....|:......:.|:.||::
  Fly   277 GLFRGLEAKILQTVLTAALMFMAYEKI 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	22/99 (22%)
		Mito_carr	134..254	CDD:395101	23/134 (17%)
		Mito_carr	262..351	CDD:395101	19/98 (19%)
PMP34	NP_728982.1	Mito_carr	15..96	CDD:395101	20/92 (22%)
		Mito_carr	105..202	CDD:395101	23/134 (17%)
		Mito_carr	214..303	CDD:395101	18/91 (20%)