Protein Alignment SLC25A14 and Shawn

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 73/351 - (20%)
• Similarity: 130/351 - (37%)
• Gaps: 90/351 - (25%)

Human    47 ASIVAEFGTFPVDLTKTRLQVQGQSI-------------------------DARFKEI-KYRGMF 85
            |.:.|.|.| |:|:.|||||.|.|::                         .|..|.. ::.|..
  Fly    50 AMVTACFMT-PLDVIKTRLQAQQQALLSNKCFLYCNGLMDHICPCGPDTPNPAAAKPAPRFSGTI 113

Human    86 HALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVE------RLEDE-------- 136
            .|..:|.:.||:.:|:||::|.|:.......|....|:..|..|.:      |..|.
  Fly   114 DAFIKISRTEGIGSLWSGLSPTLISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHP 178

Human   137 -TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRCLCSK 200
             ..|:.::.||...:::.|..:|.::::.:||:| .:....|.|:...:.|.:|..||||
  Fly   179 IPFLVPLLAGVSGRILAVTCVSPVELIRTKMQSQ-RMTHAEMFGTIRQVVQSQGVLGLWR----- 237

Human   201 AVTGCVLWLMPVIPALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILT 265
                                      |:.||..|.....|:....|:..|...   |::..|...
  Fly   238 --------------------------GLPPTILRDVPFSGIYWTCYEYLKSSF---GVVEPTFSF 273

Human   266 HFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLY----------KGTVDGILKMWKHEGF 320
            .|.:....|...|..:.|.|||:|   :::...|...::          |.....:..:::..|.
  Fly   274 SFAAGAISGSVAATITTPFDVVKT---HEQIEFGEKFIFSDNPPKQVATKSVAMRLASIYRMGGV 335

Human   321 FALYKGFWPNWLRLGPWNIIFFITYE 346
            .|::.|..|...::.|...|...::|
  Fly   336 PAIFSGLGPRLFKVAPACAIMISSFE 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	29/117 (25%)
		Mito_carr	134..254	CDD:395101	24/128 (19%)
		Mito_carr	262..351	CDD:395101	18/95 (19%)
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	29/109 (27%)
		Mito_carr	178..265	CDD:395101	23/121 (19%)
		Mito_carr	268..371	CDD:395101	18/97 (19%)