Protein Alignment SLC25A14 and sea

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 339
• Identity: 86/339 - (25%)
• Similarity: 137/339 - (40%)
• Gaps: 88/339 - (25%)

Human    39 KPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSG 103
            |..|.||:...:....|:|.:..||:||     :|.:....||.|:|..:.:...|.|.|.||.|
  Fly    35 KGIVAGGITGGIEICITYPTEYVKTQLQ-----LDEKGAAKKYNGIFDCVKKTVGERGFLGLYRG 94

Human   104 IAPALLRQASYGTI-----KIGIYQSLKRLFVERLEDETLLINMICGVVSGVISSTIA-NPTDVL 162
            ::..:     ||:|     :.|.::.||...|:.....:....::||:.:||..:.:| .|.:.:
  Fly    95 LSVLV-----YGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGVCEAIVAVTPMETI 154

Human   163 KIRM---QAQGS-LFQGSM--IGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANA 221
            |::.   |..|: .|:|..  :|..|   :.||..|:::
  Fly   155 KVKFINDQRSGNPKFRGFAHGVGQII---KSEGISGIYK-------------------------- 190

Human   222 GGSLEGVVPT----AQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALA-- 280
                 |:.||    ....||...|...:.|:.|         ||. .|..|.....|:.||:|
  Fly   191 -----GLTPTILKQGSNQAIRFFVLESLKDLYK---------GDD-HTKPVPKLVVGVFGAIAGA 240

Human   281 -----SNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNI- 339
                 :.|:|||:|||....|     ..||.|....:::.|:||..|.|||..|   |||...:
  Fly   241 ASVFGNTPLDVVKTRMQGLEA-----SKYKNTAHCAVEILKNEGPAAFYKGTVP---RLGRVCLD 297

Human   340 --IFFITYEQLKRL 351
              |.|:.|:....|
  Fly   298 VAITFMIYDSFMDL 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	28/98 (29%)
		Mito_carr	134..254	CDD:395101	24/130 (18%)
		Mito_carr	262..351	CDD:395101	31/98 (32%)
sea	NP_001027175.1	Mito_carr	34..117	CDD:395101	25/91 (27%)
		Mito_carr	125..220	CDD:395101	24/137 (18%)
		Mito_carr	235..314	CDD:395101	29/85 (34%)