Protein Alignment SLC25A14 and CG8323

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_610933.1
• Gene: CG8323 / 36566
• FlyBaseID: FBgn0033903
• Length: 303
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 95/324 - (29%)
• Similarity: 166/324 - (51%)
• Gaps: 52/324 - (16%)

Human    41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIK-YRGMFHALFRICKEEGVLALYSGI 104
            ||.|||||:.|.|.|.|:::.|||:|:||: :.||...:: |:|:.:|...:.|.:|:..|..|:
  Fly     6 FVLGGLASVGATFFTNPIEVIKTRIQLQGE-LAARGTYVEPYKGIVNAFITVAKNDGITGLQKGL 69

Human   105 APALLRQASYGTIKIGIY-QSLKRLFVERLEDETLL-INMICGVVSGVISSTIANPTDVLKIRMQ 167
            ||||..|....:.::.|| ::::|.::...:.|... :.::.|.:.||:....::|..::|.::|
  Fly    70 APALYFQFIINSFRLSIYSEAMERRWMHNRKGEVSYGMGLLWGAIGGVVGCYFSSPFFLIKTQLQ 134

Human   168 AQGSL-----FQ---GSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGS 224
            :|.:.     :|   .||..:...||.:.|.|||||
  Fly   135 SQAAKQIAVGYQHAHTSMTDALRQIYSRNGVRGLWR----------------------------- 170

Human   225 LEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGL-AGALAS---NPVD 285
              |.|....|||:..|.::..:..||..|:    ..|.:....::||:.|| ||::.|   .|.|
  Fly   171 --GSVAALPRAALGSGAQIATFGKTKALLV----QYDLVTQPTLNSFSAGLIAGSIMSVAITPPD 229

Human   286 VVRTRMMNQRA-IVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 348
            |:.||:.||.. ..|...||:|.:|..:|:.:.||.:.:|||||.|:||:.|.:.:..:.:::|
  Fly   230 VITTRLYNQGVDAEGRGLLYRGWLDCFVKILRSEGVYGMYKGFWANYLRIAPHSTLVLLFFDEL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	34/93 (37%)
		Mito_carr	134..254	CDD:395101	27/128 (21%)
		Mito_carr	262..351	CDD:395101	32/92 (35%)
CG8323	NP_610933.1	PTZ00169	5..293	CDD:240302	94/322 (29%)