Protein Alignment SLC25A14 and Ucp4B

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_608977.1
• Gene: Ucp4B / 33833
• FlyBaseID: FBgn0031758
• Length: 337
• Species: Drosophila melanogaster
• Alignment Length: 319
• Identity: 103/319 - (32%)
• Similarity: 169/319 - (52%)
• Gaps: 53/319 - (16%)

Human    51 AEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALYSGIAPALLRQASYG 115
            ||...:|.|:.|||:|:||:......::.||||:......|.:|||:|.||.||:..|.|.:.:.
  Fly    50 AEIVGYPFDMCKTRMQIQGEIASRVGQKAKYRGLLATAMGIVREEGLLKLYGGISAMLFRHSLFS 114

Human   116 TIKIGIYQSLKRLFVERLEDE----TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS-LFQG 175
            .||:..|..::...:...||.    :.|.:.|.||::|..:|.:.|||:::||:||.:|. ..:|
  Fly   115 GIKMLTYDYMREKMIVPDEDGRPQLSFLGSCISGVLAGATASVLTNPTELIKIQMQMEGQRRLRG 179

Human   176 ------SMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGSLEGVVPTAQR 234
                  :::.:...||:..|..|||:                               |.||...|
  Fly   180 EPPRIHNVLQALTSIYRTGGVVGLWK-------------------------------GTVPNTWR 213

Human   235 AAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ----- 294
            :|:|...::..||..|:.||....:.|.....||::.|.|:|.|:.|.|.|||::|:|||
  Fly   214 SALVTIGDVSCYDFCKRFLIAEFDLVDNREVQFVAAMTAGVADAILSLPADVVKSRIMNQPTDEQ 278

Human   295 -RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRLQ 352
             |.|  |   |||::|.:.::.:.|||.|:||||.|.|:|:||.:::|::|:||::|.:
  Fly   279 GRGI--H---YKGSLDCLSRLVREEGFLAMYKGFIPYWMRVGPASVVFWMTFEQIRRFR 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	28/81 (35%)
		Mito_carr	134..254	CDD:395101	32/130 (25%)
		Mito_carr	262..351	CDD:395101	39/94 (41%)
Ucp4B	NP_608977.1	Mito_carr	32..129	CDD:395101	28/78 (36%)
		Mito_carr	138..233	CDD:395101	30/125 (24%)
		Mito_carr	246..331	CDD:395101	39/89 (44%)