Protein Alignment SLC25A14 and Ucp4C

DIOPT Version :10

• Sequence 1: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Sequence 2: NP_608976.1
• Gene: Ucp4C / 33832
• FlyBaseID: FBgn0031757
• Length: 335
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 99/338 - (29%)
• Similarity: 176/338 - (52%)
• Gaps: 48/338 - (14%)

Human    27 TTVSHEMSGLN-WKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEI-KYRGMFHALF 89
            |.|:..::..| ::.:|...:.:.:||...||:|:.|||:||.|:......|.: .:|.....:.
  Fly    25 TNVADPLTARNLFQLYVNTFIGANLAESCVFPLDVAKTRMQVDGEQAKKTGKAMPTFRATLTNMI 89

Human    90 RICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLE--DETLLINMI--CGVVSGV 150
            |:   ||..:||:|.:..:.|...:.::::.:|...:|.|:.:.|  :|.|.|.|.  |...:|.
  Fly    90 RV---EGFKSLYAGFSAMVTRNFIFNSLRVVLYDVFRRPFLYQNERNEEVLKIYMALGCSFTAGC 151

Human   151 ISSTIANPTDVLKIRMQAQGSLFQ-------GSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLW 208
            |:..:|||.|::|:|||.:|...|       .||:.:|:|||::.|
  Fly   152 IAQALANPFDIVKVRMQTEGRRRQLGYDVRVNSMVQAFVDIYRRGG------------------- 197

Human   209 LMPVIPALWEANAGGSLEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTC 273
                :|::|        :||.|:..||.::...::..|||:|:.......:.:.:...||||...
  Fly   198 ----LPSMW--------KGVGPSCMRACLMTTGDVGSYDISKRTFKRLLDLEEGLPLRFVSSMCA 250

Human   274 GLAGALASNPVDVVRTRMMNQRAIVGHVDL-YKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPW 337
            ||..::.|.|.||:::|||||.......:| ||.::|.:.|:.:.||...||||..|.|.||||:
  Fly   251 GLTASVLSTPADVIKSRMMNQPVDESGKNLYYKNSLDCVRKLVREEGVLTLYKGLMPTWFRLGPF 315

Human   338 NIIFFITYEQLKR 350
            :::|:::.|||::
  Fly   316 SVLFWLSVEQLRQ 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	25/97 (26%)
		Mito_carr	134..254	CDD:395101	36/130 (28%)
		Mito_carr	262..351	CDD:395101	36/90 (40%)
Ucp4C	NP_608976.1	Mito_carr	49..124	CDD:395101	21/77 (27%)
		Mito_carr	137..232	CDD:395101	34/125 (27%)
		Mito_carr	237..329	CDD:395101	36/92 (39%)